Unique ID issued by UMIN | UMIN000029135 |
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Receipt number | R000033312 |
Scientific Title | Endothelial Disorder in Lifestyle-related diseases |
Date of disclosure of the study information | 2017/11/01 |
Last modified on | 2020/03/03 22:20:30 |
Endothelial Disorder in Lifestyle-related diseases
Endothelial Disorder in Lifestyle-related diseases
Endothelial Disorder in Lifestyle-related diseases
Endothelial Disorder in Lifestyle-related diseases
Japan |
Lifestyle-related diseases
Medicine in general | Cardiology | Adult |
Others
NO
Measurement of Syndecan-1 in Medical Checkup
Others
N/A
Others
Others
Not applicable
Measurement of Syndecan-1 in Medical Checkup
Observational
20 | years-old | <= |
100 | years-old | > |
Male and Female
Above 20 years old
Less than 20 years old
1000
1st name | Hideshi |
Middle name | |
Last name | Okada |
Gifu University Hospital
Advanced Critical Care Center
501-1194
1-1, Yanagido, Gifu Japan
058-230-6448
edm2@gifu-u.ac.jp
1st name | Hideshi |
Middle name | |
Last name | Okada |
Gifu University Hospital
Advanced Critical Care Center
501-1194
1-1, Yanagido, Gifu Japan
058-230-6448
edm2@gifu-u.ac.jp
Gifu University
Asahi University
Other
Gifu University Graduate School of Medicine
1-1 YANAGIDO
058-230-6059
rinri@gifu-u.ac.jp
NO
2017 | Year | 11 | Month | 01 | Day |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780947/pdf/jcm-08-01320.pdf
Published
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780947/pdf/jcm-08-01320.pdf
159
The participants enrolled in this study were 1312 patients who underwent comprehensive medical examinations at Asahi University Hospital from Jan 2018 to Jun 2018. At enrollment, blood samples were obtained and study personnea collected demographic and clinical data. According to nonlinear regression, the concentrations of serum syndecan-1 were significantly related to age, AST, BUN, triglyceride concentration and hematocrit. These relationships were independent associations.
2020 | Year | 03 | Month | 03 | Day |
2019 | Year | 08 | Month | 27 | Day |
Between January and June 2018, we enrolled 1313 patients. One patient undergoing hemodialysis was excluded from the study, thus, we included 1312 patients, with a median age of 51 years in this study.
Ethical permission was obtained from the medical permission committee of Gifu University Graduate School of Medicine, Gifu, Japan (record no. : 29-214) and Asahi University, Japan (record no. : 30-29), and all patients provided written informed consent.
None
A priori, we chose to include age, sex, BMI, systolic blood pressure, serum total protein, albumin, total bilirubin, aspartic aminotransferase concentration (AST), alanine transaminase, lactate dehydrogenase, blood urea nitrogen (BUN), creatinine concentration, CRP, fasting blood sugar concentration, hemoglobin a1c, serum triglyceride, high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, uric acid concentration, hemoglobin concentration, hematocrit (Ht), white blood cell number, and platelet number in the regression model. To avoid bias in the results by excluding missing data, we used multiple imputations in the regression model.
Completed
2017 | Year | 09 | Month | 06 | Day |
2017 | Year | 09 | Month | 06 | Day |
2018 | Year | 01 | Month | 01 | Day |
2018 | Year | 06 | Month | 30 | Day |
2018 | Year | 12 | Month | 03 | Day |
2018 | Year | 12 | Month | 31 | Day |
2019 | Year | 02 | Month | 12 | Day |
N/A
2017 | Year | 09 | Month | 13 | Day |
2020 | Year | 03 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000033312
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