Unique ID issued by UMIN | UMIN000029310 |
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Receipt number | R000033489 |
Scientific Title | Impact of anti-PCSK9 antibody Alirocumab on lipid-lowering on patient motivation to treatment for hypercholesterolemia. |
Date of disclosure of the study information | 2017/10/01 |
Last modified on | 2017/10/16 11:15:23 |
Impact of anti-PCSK9 antibody Alirocumab on lipid-lowering on patient motivation to treatment for hypercholesterolemia.
Impact of Alirocumab on patient motivation to treatment.
Impact of anti-PCSK9 antibody Alirocumab on lipid-lowering on patient motivation to treatment for hypercholesterolemia.
Impact of Alirocumab on patient motivation to treatment.
Japan |
Dyslipidemia
Diabetes mellitus
Endocrinology and Metabolism |
Others
NO
To investigate the impact of Alirocumab on lipid-lowering on patient satisfaction and motivation to treatment in patient with hypercholesterolemia.
Safety,Efficacy
Not applicable
Change in patient satisfaction and motivation to treatment from baseline to follow-up as scored using questionnaire.
glucose(fasting),
HbA1c,AST,ALT,gamma-GTP,BUN,Cr,CK,TC,LDL-C,HDL-C,TG,Na,K,Cl,Lp(a),hs-CRP
Carotid artery ultrasound,PWV
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
To administrate Alirocumab to patients who have inadequate management of LDL-C levels on maximum tolerated dose
20 | years-old | <= |
Not applicable |
Male and Female
1)Patients with Type1 or Type2 diabetes mellitus
2)Patients with heterozygous familial hypercholesterolemia or hypercholesterolemia at high-cardiovascular risk,who have inadequate management of LDL-C levels on maximum tolerated dose of statin
3)Patients aged equal or over 20 years
1)Pregnant
2)Drug allergy to Alirocumab
3)Unsuitable patients for this study by physicians decision
10
1st name | |
Middle name | |
Last name | Yasuro Kumeda |
Minamiosaka Hospital
Department of Internal Medicine
1-18-18, Higashikagaya, Suminoe-ku, Osaka, 559-0012, Japan
06-6685-0221
y_kumeda@yahoo.co.jp
1st name | |
Middle name | |
Last name | Yuji Kawaguchi |
Minamiosaka Hospital
Department of Internal Medicine
1-18-18, Higashikagaya, Suminoe-ku, Osaka, 559-0012, Japan
06-6685-0221
y.kawaguchi@minamiosaka.com
Minamiosaka Hospital
Department of Internal Medicine
none
Self funding
NO
2017 | Year | 10 | Month | 01 | Day |
Unpublished
Open public recruiting
2017 | Year | 09 | Month | 26 | Day |
2017 | Year | 10 | Month | 01 | Day |
2017 | Year | 09 | Month | 27 | Day |
2017 | Year | 10 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000033489
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