Unique ID issued by UMIN | UMIN000029313 |
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Receipt number | R000033511 |
Scientific Title | Feasibility study of Carbon-Ion Radiotherapy for Re-Irradiation of Locoregionally Recurrent or Metastatic Lung Tumors |
Date of disclosure of the study information | 2017/09/28 |
Last modified on | 2018/03/29 08:30:47 |
Feasibility study of Carbon-Ion Radiotherapy for Re-Irradiation of Locoregionally Recurrent or Metastatic Lung Tumors
Carbon-Ion Radiotherapy for Re-Irradiation
Feasibility study of Carbon-Ion Radiotherapy for Re-Irradiation of Locoregionally Recurrent or Metastatic Lung Tumors
Carbon-Ion Radiotherapy for Re-Irradiation
Japan |
Lung cancer or metastatic lung tumor
Radiology |
Malignancy
NO
To evaluate the toxicity and efficacy of re-irradiation with CIRT for locoregionally recurrent, metastatic, or secondary lung tumors
Safety
Toxicity
Observational
0 | years-old | <= |
999 | years-old | >= |
Male and Female
1) patients who received re-irradiation with CIRT
2) measurable tumors
3) a performance status of 0-2
4) no systemic therapy, such as chemotherapy, within 1 month of commencing re-irradiation with CIRT
5) an estimated life expectancy of more than 6 months
The presence of other primary cancers
95
1st name | |
Middle name | |
Last name | Kazuhiko Hayashi |
National Institutes for Quantum and Radiological Sciences and Technology
Hospital of the National Institute of Radiological Sciences
Anagawa 4-9-1, Inage-ku 263-8555 Chiba, Japan
043-206-3360
hayashi.kazuhiko@qst.go.jp
1st name | |
Middle name | |
Last name | Kazuhiko Hayashi |
National Institutes for Quantum and Radiological Sciences and Technology
Hospital of the National Institute of Radiological Sciences
Anagawa 4-9-1, Inage-ku 263-8555 Chiba, Japan
043-206-3360
hayashi.kazuhiko@qst.go.jp
Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Sciences and Technology
Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Sciences and Technology
Other
NO
2017 | Year | 09 | Month | 28 | Day |
Published
https://www.ncbi.nlm.nih.gov/pubmed/29498145
Data of 95 patients with prior intrathoracic carbon-ion radiotherapy who were treated with reirradiation with carbon-ion radiotherapy at our institution between 2006 and 2016 were retrospectively analyzed. Regarding severe toxicities, 1 patient experienced each of the following. Grade 5 bronchopleural fistula, Grade 4 radiation pneumonitis, Grade 3 chest pain, and Grade 3 radiation pneumonitis. The 2-year local control and overall survival rates were 54.0% and 61.9%, respectively. In conclusion, reirradiation with carbon-ion radiotherapy was associated with relatively low toxicity and moderate efficacy.
Completed
2017 | Year | 09 | Month | 27 | Day |
2017 | Year | 10 | Month | 09 | Day |
2017 | Year | 10 | Month | 31 | Day |
None
2017 | Year | 09 | Month | 27 | Day |
2018 | Year | 03 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000033511
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