Unique ID issued by UMIN | UMIN000030525 |
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Receipt number | R000034846 |
Scientific Title | Study for development of new treatment for antibody mediated rejection in organ transplantation |
Date of disclosure of the study information | 2018/01/09 |
Last modified on | 2018/12/24 09:54:51 |
Study for development of new treatment for antibody mediated rejection in organ transplantation
Development of new treatment for antibody mediated rejection
Study for development of new treatment for antibody mediated rejection in organ transplantation
Development of new treatment for antibody mediated rejection
Japan |
organ failure
Surgery in general |
Others
NO
To avoid or to treat antibody mediated rejection through depletion of B cells by anti CD20 antibody
Safety,Efficacy
Confirmatory
Pragmatic
Not applicable
Incidence of diminishment of HLA antibody in desensitization
changes of clinico-pathological findings in treatment
Change of HLA antibody titers
incidence of AMR
incidence of ACR
patient and graft survival
organ functions
adverse effects
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
NO
NO
Institution is not considered as adjustment factor.
NO
1
Treatment
Medicine |
Administration with rituximab
375 mg/m2 once or twice
Not applicable |
Not applicable |
Male and Female
Patients with preoperative sensitization or with AMR
Patients treated in registered institutions
Patients eating or after organ transplantation (liver, heart, lung, pancreas, islet cells, small bowel)
Patients who wish to participate this study for him/herself or whose gardens or representatives.
Patients with active infections, or malignancy, or patients whom the responsible person decided to be not appropriate.
41
1st name | |
Middle name | |
Last name | Hiroto Egawa |
Tokyo Women's Medical University
Department of Surgery
8-1 Shinjuku-ku, Kawada-cho, Tokyo
03-3353-8111
egawa.hiroto@twmu.ac.jp
1st name | |
Middle name | |
Last name | Hiroto Egawa |
Tokyo Women's Medical University
Department of Surgery
8-1 Shinjuku-ku, Kawada-cho, Tokyo
03-3353-8111
egawa.hiroto@twmu.ac.jp
Tokyo Women's Medical University
AMED
Japanese Governmental office
NO
2018 | Year | 01 | Month | 09 | Day |
Unpublished
Enrolling by invitation
2018 | Year | 03 | Month | 01 | Day |
2018 | Year | 03 | Month | 01 | Day |
2017 | Year | 12 | Month | 22 | Day |
2018 | Year | 12 | Month | 24 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000034846
Research Plan | |
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Research case data | |
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