Unique ID issued by UMIN | UMIN000030878 |
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Receipt number | R000035255 |
Scientific Title | Effect of Diet and Exercise Therapy on Circulating Extracellular Vesicles |
Date of disclosure of the study information | 2018/01/19 |
Last modified on | 2023/01/23 16:27:10 |
Effect of Diet and Exercise Therapy on Circulating Extracellular Vesicles
Diet/Exercise and EVs
Effect of Diet and Exercise Therapy on Circulating Extracellular Vesicles
Diet/Exercise and EVs
Japan |
Obesity, Non alcoholic fatty liver diseases (NAFLD)
Hepato-biliary-pancreatic medicine | Endocrinology and Metabolism |
Others
NO
To Clarify the effects of diet/exercise therapy on cytokines, extracellular vesicles (EVs) and metabolic parameters in obese children and patients with non -alcoholic fatty liver disease (NAFLD)
Efficacy
Anthropometric data, body composition data and circulating EV number and component after receiving diet and exercise therapy,
Adipokines, myokines and hepatokines, lipid and glucose metabolism markers, and liver and kidney function markers after diet and exercise therapy.
Interventional
Parallel
Non-randomized
Open -no one is blinded
No treatment
2
Treatment
Device,equipment | Behavior,custom |
Restriction of calorie intake and exercise for more than 6 months in obese children and patients with NAFLD.
Approximately 20 minutes of exercise using ergometer (once per tested person)
6 | years-old | <= |
Not applicable |
Male and Female
(1) Children (6 to 18 years) who receive the lecture for health and obtain informed consent at Mie National Hospital.
(2) Children (9 to 15 years) who attend the healthy camp and obtain informed consent at Mie National Hospital.
(3) Children (6 to 18 years) who received diet and exercise therapy and obtain informed consent at Mie National Hospital.
(4) Patients with NAFLD (equal or more than 18 years) who received diet and exercise therapy and obtain informed consent at Mie University Hospital.
(5) Healthy students of Mie University who perform exercise training routinely and obtain informed consent.
(1) Subjects who cannot declare their intention.
(2) Subjects whom doctors or researchers judged as inappropriate for the study.
250
1st name | Yoshinao |
Middle name | |
Last name | Kobayashi |
Mie University
Center for Physical and Mental Health
514-8507
1577 Kurimamachiya-cyo, Tsu, Mie 514-8507, Japan
059-231-5375
yoshinao@hac.mie-u.ac.jp
1st name | Yoshinao |
Middle name | |
Last name | Kobayashi |
Mie University
Center for Physical and Mental Health
514-8507
1577 Kurimamachiya-cyo, Tsu, Mie 514-8507, Japan
059-231-5375
yoshinao@hac.mie-u.ac.jp
Center for Physical and Mental Health, Mie University
MEXT (Japan)
Japanese Governmental office
Mie National Hospital
Ethic Committee at Mie University Hospital
2-174 Edobashi, Tsu, Mie 514-8507, Japan
059-232-5045
s-kenkyu@mo.medic.mie-u.ac.jp
NO
2018 | Year | 01 | Month | 19 | Day |
Unpublished
Open public recruiting
2018 | Year | 01 | Month | 11 | Day |
2018 | Year | 01 | Month | 11 | Day |
2018 | Year | 01 | Month | 19 | Day |
2026 | Year | 03 | Month | 31 | Day |
2018 | Year | 01 | Month | 18 | Day |
2023 | Year | 01 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000035255
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