Unique ID issued by UMIN | UMIN000031428 |
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Receipt number | R000035410 |
Scientific Title | Effect of preemptive duloxetine for postoperative pain |
Date of disclosure of the study information | 2018/04/11 |
Last modified on | 2020/08/25 10:35:12 |
Effect of preemptive duloxetine for postoperative pain
Duloxetine for postoperative pain
Effect of preemptive duloxetine for postoperative pain
Duloxetine for postoperative pain
Japan |
Low back pain
Orthopedics |
Others
NO
To examine whether preemptive administration of duloxetine reduces postoperative pain.
Safety
Postoperative pain using visual analogue scale
Consumption of postoperative analgesics
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Active
2
Treatment
Medicine |
Duloxetine (40 mg) will be orally administered 2h before surgery, then postoperative pain will be assessed.
Diazepam (4 mg) will be orally administered 2h before surgery as active placebo group.
20 | years-old | <= |
80 | years-old | >= |
Male and Female
Patients scheduled to undergo posterior lumbar interbody fusion will be enrolled in this study. The study population included patients aged 20-80 years who are American Society of Anesthesiologists physical status I-II and who agreed to participate in this clinical trial.
1) Patients who can not use duloxetine
2) Patients who need antipsychotics or antidepressants and who are schizophrenia, bipolar disease, or depression within a year before registration of this study.
3) Patients who needs opioids
4) Patinets who can not agree the protocol.
66
1st name | Hideaki |
Middle name | |
Last name | Obata |
Fukushima Medical University Hospital
Center for Pain Management
960-1295
Hikarigaoka 1, Fukushima-city, Fukushima, 960-1295
024-547-1111
obata@fmu.ac.jp
1st name | Hideaki |
Middle name | |
Last name | Obata |
Fukushima Medical University Hospital
Center for Pain Management
960-1295
Hikarigaoka 1, Fukushima-city, Fukushima, 960-1295
024-547-1111
obata@fmu.ac.jp
Fukushima Medical University Hospital
Fukushima Medical University Hospital
Local Government
Fukushima Medical University Hospital
Hikarigaoka 1, Fukushima-city, Fukushima, 960-1295
024-547-1111
r-gyomu@fmu.ac.jp
NO
慶友整形外科病院(群馬県)
2018 | Year | 04 | Month | 11 | Day |
Unpublished
Terminated
2018 | Year | 05 | Month | 23 | Day |
2018 | Year | 05 | Month | 23 | Day |
2018 | Year | 05 | Month | 23 | Day |
2019 | Year | 03 | Month | 29 | Day |
2018 | Year | 02 | Month | 22 | Day |
2020 | Year | 08 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000035410
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