Unique ID issued by UMIN | UMIN000031535 |
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Receipt number | R000035984 |
Scientific Title | Analysis of differentiation of antiEGFR antibody in the 1st line chemotherapy with mFOLFOX6 in RAS-wild metastatic colorectal cancer. |
Date of disclosure of the study information | 2018/04/01 |
Last modified on | 2018/03/01 16:01:28 |
Analysis of differentiation of antiEGFR antibody in the 1st line chemotherapy with mFOLFOX6 in RAS-wild metastatic colorectal cancer.
Differentiation of cetuximab and panitumumab in 1st line chemotherapy of RAS-wild mCRC.
Analysis of differentiation of antiEGFR antibody in the 1st line chemotherapy with mFOLFOX6 in RAS-wild metastatic colorectal cancer.
Differentiation of cetuximab and panitumumab in 1st line chemotherapy of RAS-wild mCRC.
Japan |
metastatic colorectal cancer
Gastroenterology | Gastrointestinal surgery |
Malignancy
YES
To analyze the difference of clinical effects and safety of cetuximab and panitumumab in patients with RAS wild-type advanced colorectal cancer
Safety,Efficacy
Confirmatory
Pragmatic
Phase IV
response rate
safety
relapse-free survival
overall survival
early tumor shurinkage
neutrophil to lymphocyte ratio
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
mFOLFOX6+cetuximab or panitumumab
20 | years-old | <= |
Not applicable |
Male and Female
pathologically proven colorectal cancer
RAS wild type
PS; 0-2
untreated case
severe dysfunctions of vital organs
no prior radiotherapy, chemotherapy
no other co-existing malignancy within the last five years
no severe concurrent medical or psychiatric illnessno hypersensitivity to the study drugs
50
1st name | |
Middle name | |
Last name | Dai Manaka |
Kyoto Katsura Hospital
Department of Surgery, Gastro-Intestinal Center
17 Yamada Hirao-cho, Nishikyo-ku, Kyoto
075-391-5811
d_manaka@katsura.com
1st name | |
Middle name | |
Last name | Dai Manaka |
Kyoto Katsura Hospital
Department of Surgery, Gastro-Intestinal Center
17 Yamada Hirao-cho, Nishikyo-ku, Kyoto
075-391-5811
d_manaka@katsura.com
Kyoto Katsura Hospital
Kyoto Katsura Hospital
Self funding
NO
2018 | Year | 04 | Month | 01 | Day |
Unpublished
No longer recruiting
2012 | Year | 04 | Month | 01 | Day |
2013 | Year | 01 | Month | 01 | Day |
2018 | Year | 03 | Month | 01 | Day |
2018 | Year | 03 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000035984
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