Unique ID issued by UMIN | UMIN000031558 |
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Receipt number | R000036033 |
Scientific Title | Effects of nutrient in Japanese subjects with knee pain: a randomized, double-blind, placebo-controlled, parallel pilot study. |
Date of disclosure of the study information | 2018/03/02 |
Last modified on | 2018/05/08 11:13:02 |
Effects of nutrient in Japanese subjects with knee pain: a randomized, double-blind, placebo-controlled, parallel pilot study.
Effects of nutrient in Japanese subjects with knee pain
Effects of nutrient in Japanese subjects with knee pain: a randomized, double-blind, placebo-controlled, parallel pilot study.
Effects of nutrient in Japanese subjects with knee pain
Japan |
Knee pain
Orthopedics | Rehabilitation medicine |
Others
NO
To investigate the effect of nutrient intake on knee pain.
Efficacy
Confirmatory
Pragmatic
Phase II
VAS score of knee pain, JKOM score
Blood metabolite concentrations, Blood enzyme activities
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
NO
2
Treatment
Food |
Active supplement (continuous intake for 12W)
Placebo supplement (continuous intake for 12W)
45 | years-old | <= |
70 | years-old | >= |
Male and Female
-Subjects who have high scores of JKOM(II-V)
-Subjects who have therapeutic history for at least 2 year for knee joint pain
-Subjects who suffer from articular rheumatism
-Subjects who suffer from liver or kidney disease
-Subjects who have therapeutic history for serious liver, kidney or heart disease
-Subjects who have medication for knee joint pain (anodyne, anti-inflammation)
-Subjects who have therapeutic history for at least 1 year for serious locomotor system (for example, a fracture, a tendon rapture, a pulled muscle)
-Subjects who take excess alcohol
-Subjects who take supplement including chondroitin sulfate or glucosamine for knee joint pain in daily
-Subjects who are not eligible due to physician's judgment
50
1st name | |
Middle name | |
Last name | Shingo Kakuo |
Kao Corporation
Biological Science Laboratory
2606 Akabane, Ichikai-Machi, Haga-Gun, Tochigi
+81-285-68-7440
kakuo.shingo@kao.com
1st name | |
Middle name | |
Last name | Shingo Kakuo |
Kao Corporation
Biological Science Laboratory
2606 Akabane, Ichikai-Machi, Haga-Gun, Tochigi
+81-285-68-7440
kakuo.shingo@kao.com
SOUKEN Laboratories
Kao Corporation
Profit organization
NO
芝パレスクリニック (Shiba Palace Clinic)(東京都)
2018 | Year | 03 | Month | 02 | Day |
Published
https://doi.org/10.1007/s40520-018-0953-6
-Continuous intake of active nutrient significantly lowered VAS score of knee pain.
-Continuous intake of active nutrient significantly relieved knee pain and stiffness.
Aging Clinical and Experimental Research
(https://doi.org/10.1007/s40520-018-0953-6)
Completed
2011 | Year | 09 | Month | 28 | Day |
2011 | Year | 10 | Month | 01 | Day |
2012 | Year | 05 | Month | 22 | Day |
2018 | Year | 03 | Month | 02 | Day |
2018 | Year | 05 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000036033
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