Unique ID issued by UMIN | UMIN000031904 |
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Receipt number | R000036428 |
Scientific Title | Influence of "Soshinmei" drink containing ginkgo biloba extract on cerebral blood flow |
Date of disclosure of the study information | 2018/04/01 |
Last modified on | 2020/01/20 11:41:44 |
Influence of "Soshinmei" drink containing ginkgo biloba extract on cerebral blood flow
Influence of drink containing ginkgo biloba extract on cerebral blood flow
Influence of "Soshinmei" drink containing ginkgo biloba extract on cerebral blood flow
Influence of drink containing ginkgo biloba extract on cerebral blood flow
Japan |
Healthy people belonging to qi deficiency or qi stagnation in the TCM quality table
Adult |
Others
NO
Major ingredients of ginkgo biloba extract include flavonoids and ginkgolides. Flavonoids have several functions such as dilatation of vessel s, improvement of arteriosclerosis, Antispasmodic action and normalization of blood glucose level. Ginkgolides can mainly improve peripheral microcirculation, especially has a good function of improving cerebral and peripheral vascular circulation. Therefore, improvement of dementia, hypertension, tinnitus, neuralgia, polyuria, coldness, and allergies. In this study, a non-invasive examination device, NIRS is used to observe the effect of drink containing ginkgo leaf extract on cerebral blood flow.
Efficacy
Confirmatory
Explanatory
Not applicable
Changes of hemoglobin concentration in the anterior cortex 1 hour after taking the drink containing ginkgo biloba extract
Changes of condition based on the Japanese version of Chinese Medicine Quality Inquiry Form(CCMQ-J)
Changes of subjective symptoms(NRS)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Prevention
Food |
Single intake of 50 ml of "Soshinmei" drink that contains curcumin, gingko leaf extract, carnitine, pickpea extract, glycosyl transfer hesperidin
18 | years-old | <= |
Not applicable |
Male and Female
Healthy people belonging to qi deficiency or qi stagnation in the Japanese CCMQ-J
Persons who visit psychiatric or psychosomatics department
Persons taking psychotropics (antipsychotics, anxiolytics, antidepressants, antimanics, sleep induction drugs, etc.)
Persons who have a history of cerebrovascular diseases
Persons who continuously take health food for stress
Persons taking antiplatelet drugs, anticoagulants (warfarin etc.) during the test period
Persons who are easy to bleed
40
1st name | Ko |
Middle name | |
Last name | Nishimura |
Suzuka University of Medical Science
Institute of Traditional Chinese Medicine
510-0226
1275-3, Kishioka, Suzuka-city, Mie, 510-0226, JAPAN
059-381-2385
ko-n@suzuka-u.ac.jp
1st name | Ken |
Middle name | |
Last name | Takagi |
Suzuka University of Medical Science
Institute of Traditional Chinese Medicine
510-0226
1275-3, Kishioka, Suzuka-city, Mie, 510-0226, JAPAN
059-381-2385
Takagi17@suzuka-u.ac.jp
Suzuka University of Medical Science
Institute of Traditional Chinese Medicine
Zenyaku Kogyo Co., Ltd.
Profit organization
Institute of Traditional Chinese Medicine, Suzuka University of Medical Science
1275-3, Kishioka, Suzuka-city, Mie, 510-0226, JAPAN
059-381-2385
ko-n@suzuka-u.ac.jp
NO
2018 | Year | 04 | Month | 01 | Day |
Unpublished
47
Integrated value of oxygenated hemoglobin in the frontal lobe by NIRS at 1 hour after intake of drink containing ginkgo biloba extract significantly decreased. Yang deficiency, yin deficiency, sputum wet, wet heat, and blood stagnation constitutions significantly improved after intake. As for subjective symptoms, physical fatigue and mental symptoms significantly improved. There were no adverse events with drinking.
2020 | Year | 01 | Month | 20 | Day |
Completed
2018 | Year | 03 | Month | 20 | Day |
2018 | Year | 02 | Month | 28 | Day |
2018 | Year | 04 | Month | 06 | Day |
2020 | Year | 03 | Month | 31 | Day |
2018 | Year | 03 | Month | 26 | Day |
2020 | Year | 01 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000036428
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