UMIN-CTR Clinical Trial

BACK TOP
UMIN-CTR English Home Glossary (Simple) FAQ Search clinical trials

Name:
UMIN ID:

Recruitment status Main results already published
Unique ID issued by UMIN UMIN000032524
Receipt No. R000037094
Scientific Title Effect of coffee chlorogenic acid in grade I hypertension and high-normal blood pressure on blood pressure: a meta-analysis using individual participant data
Date of disclosure of the study information 2018/05/20
Last modified on 2018/11/08

* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments


Basic information
Public title Effect of coffee chlorogenic acid in grade I hypertension and high-normal blood pressure on blood pressure: a meta-analysis using individual participant data
Acronym A individual participant data meta-analysis of coffee chlorogenic acid.
Scientific Title Effect of coffee chlorogenic acid in grade I hypertension and high-normal blood pressure on blood pressure: a meta-analysis using individual participant data
Scientific Title:Acronym A individual participant data meta-analysis of coffee chlorogenic acid.
Region
Japan

Condition
Condition in grade I hypertension and high-normal blood pressure
Classification by specialty
Cardiology Adult
Classification by malignancy Others
Genomic information NO

Objectives
Narrative objectives1 This individual participant data (IPD) meta-analysis was to assess the overall effect of coffee chlorogenic acid supplementation on grade 1 hypertension and high-normal blood pressure.
Basic objectives2 Efficacy
Basic objectives -Others
Trial characteristics_1 Confirmatory
Trial characteristics_2
Developmental phase

Assessment
Primary outcomes blood pressure (systolic blood pressure and diastolic blood pressure)
Key secondary outcomes

Base
Study type Others,meta-analysis etc

Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment

Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10

Eligibility
Age-lower limit
20 years-old <=
Age-upper limit

Not applicable
Gender Male and Female
Key inclusion criteria Randomized controlled trials.

Participant: Grade I hypertension and/or high-normal blood pressure without treatments.
Intervention: Ingestion of coffee chlorogenic acid for 12 or more weeks.
Comparison: Placebo.
Outcome: Blood pressure.
Key exclusion criteria Studies, which do not meet Key inclusion criteria were exclude
Target sample size 100

Research contact person
Name of lead principal investigator
1st name
Middle name
Last name Kazuya Kozuma
Organization Kao Corporation
Division name Health Care Food Research lab
Zip code
Address 2-1-3, Bunka, Sumida-ku, Tokyo
TEL 03-563-7476
Email kouzuma.kazuya@kao.com

Public contact
Name of contact person
1st name
Middle name
Last name Kazuya Kozuma
Organization Kao Corporation
Division name Health Care Food Research Labs.
Zip code
Address 2-1-3, Bunka, Sumida-ku, Tokyo
TEL 03-563-7476
Homepage URL
Email kouzuma.kazuya@kao.com

Sponsor
Institute Kao Corporation
Institute
Department

Funding Source
Organization Kao Corporation
Organization
Division
Category of Funding Organization Profit organization
Nationality of Funding Organization

Other related organizations
Co-sponsor
Name of secondary funder(s)

IRB Contact (For public release)
Organization
Address
Tel
Email

Secondary IDs
Secondary IDs NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW

Institutions
Institutions

Other administrative information
Date of disclosure of the study information
2018 Year 05 Month 20 Day

Related information
URL releasing protocol
Publication of results Published

Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Kozuma et al.
Effect of coffee chlorogenic acid in grade I hypertension and high-normal blood pressure Japanese adults on blood pressure: a meta-analysis using individual participant data from randomized controlled trials.
Jpn Pharmacol Ther. 2018; 46: 1157-1166

Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description

Progress
Recruitment status Main results already published
Date of protocol fixation
2018 Year 04 Month 25 Day
Date of IRB
Anticipated trial start date
2018 Year 05 Month 09 Day
Last follow-up date
Date of closure to data entry
Date trial data considered complete
Date analysis concluded

Other
Other related information Data sources
Medline (PubMed), JDream3 and University hospital Medical Information Network Clinical Trials Registry (UMIN-CTR)

Management information
Registered date
2018 Year 05 Month 09 Day
Last modified on
2018 Year 11 Month 08 Day


Link to view the page
URL(English) https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037094

Research Plan
Registered date File name

Research case data specifications
Registered date File name

Research case data
Registered date File name


Contact us.