Unique ID issued by UMIN | UMIN000032584 |
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Receipt number | R000037156 |
Scientific Title | Altered neural synchronization to pure tone stimulation in patients with mesial temporal lobe epilepsy: An MEG study |
Date of disclosure of the study information | 2018/05/14 |
Last modified on | 2022/05/17 11:05:05 |
Altered neural synchronization to pure tone stimulation in patients with mesial temporal lobe epilepsy: An MEG study
AEF in epilepsy
Altered neural synchronization to pure tone stimulation in patients with mesial temporal lobe epilepsy: An MEG study
AEF in epilepsy
Japan |
Epilepsy
Neurology | Adult |
Others
NO
To examine whether neural synchronization induced by monaural pure tone stimulation provides useful diagnostic information about epileptic foci in unilateral mTLE patients
Efficacy
Group effect of neural synchronization
Interventional
Parallel
Non-randomized
Open -no one is blinded
No treatment
3
Diagnosis
Device,equipment |
monaural auditory stimuli: left and right ear to normal control.
monaural auditory stimuli: left and right ear to left temporal lobe epilepsy.
monaural auditory stimuli: left and right ear to right temporal lobe epilepsy.
20 | years-old | <= |
65 | years-old | >= |
Male and Female
For patient group: Secondary usage of previous study. Patients with temporal lobe epilepsy whose MEG was available from 2012 to 2021.
For control group: Secondary usage fo previous study.
History of severe head trauma, psychiatric diseases, MMSE under 26, alchoholic/drug dependence.
60
1st name | Shozo |
Middle name | |
Last name | Tobimatsu |
Kyushu university
clinical neurophysiology
812-8582
3-1-1 Maidashi, Higashi-ku, Fukuoka-city
092-642-5543
teppei_m2002@yahoo.co.jp
1st name | Teppei |
Middle name | |
Last name | Matsubara |
Kyushu university, Faculty of Medicine
Clinical Neurophysiology
812-8582
3-1-1 Maidashi, Higashi-ku, Fukuoka-city
092-642-5543
teppei_m2002@yahoo.co.jp
Kyushu university, department of clinical neurophysiology
MEXT
Japanese Governmental office
IRB Kyushu University
WW6 615, 3-1-1 Maidashi, Fukuoka
092-642-5082
bynintei@jimu.kyushu-u.ac.jp
NO
2018 | Year | 05 | Month | 14 | Day |
https://www.med.kyushu-u.ac.jp/neurophy/
Published
10.1016/j.yebeh.2018.08.036
71
The M100 amplitude revealed that patients with right mTLE exhibited smaller M100 amplitude than patients with left mTLE and HCs. Decreased PLFs in the alpha band observed in patients with right mTLE compared with those (PLFs) in patients with left mTLE. Right hemispheric predominance was confirmed in both HCs and patients with left mTLE while patients with right mTLE showed a lack of right hemispheric predominance.
2022 | Year | 05 | Month | 17 | Day |
39 TLE, 32 healthy control
Recruited through HP
None
MEG recording (M100 amplitude, phase-locking factor, phase-locking value)
Completed
2018 | Year | 05 | Month | 14 | Day |
2016 | Year | 03 | Month | 18 | Day |
2018 | Year | 05 | Month | 14 | Day |
2019 | Year | 03 | Month | 31 | Day |
2018 | Year | 05 | Month | 14 | Day |
2022 | Year | 05 | Month | 17 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037156
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