Unique ID issued by UMIN | UMIN000032653 |
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Receipt number | R000037231 |
Scientific Title | Efficacy of oral steroids to treat the immediate symptoms of food allergy |
Date of disclosure of the study information | 2018/05/20 |
Last modified on | 2022/08/11 17:12:03 |
Efficacy of oral steroids to treat the immediate symptoms of food allergy
Efficacy of steroids to treat the immediate symptoms of food allergy
Efficacy of oral steroids to treat the immediate symptoms of food allergy
Efficacy of steroids to treat the immediate symptoms of food allergy
Japan |
Food Allergy
Clinical immunology | Pediatrics |
Others
NO
To evaluate the efficacy of steroids to treat the immediate symptoms of food allergy.
Efficacy
The ratio of patients who experienced a worsening the ASCA total score by 10 points or more until the end of the oral food challenge according to intention to treat analysis
The ratio of patients who experienced a worsening the ASCA total score by 10 points or more until the end of the oral food challenge according to per protocol analysis.
The ratio of patients who experienced a worsening the ASCA total score by 10 points or more until the end of the oral food challenge, while excluding cases where the ASCA score deteriorated by 10 points or more before the administration of any drugs.
The analysis of the efficacy of steroids was stratified according to each organ symptom.
The efficacy of the steroids to suppress anaphylaxis and anaphylaxy shock.
The analysis of the efficacy of steroids corrected by age, sex, past history of asthma and atopic dermatitis, antigen specific-IgE titer etc.
Interventional
Parallel
Randomized
Cluster
Open -no one is blinded
Active
2
Treatment
Medicine |
Taking both anti-histamines and 1 mg/kg predonisolone
Taking anti-histamins
Not applicable |
18 | years-old | >= |
Male and Female
Patients who have undergone oral food challenge tests, and demonstrated a symptom score of 10 (skin symptom) or 11 (10 of skin symptom plus 1)according to the Anaphylaxis Scoring Aichi (ASCA).
Patients who have a poor physical condition, such as suffering from a cold before undergoing the oral food challenge tests.
Patients who had orally taken antihistamines, leukotriene receptor antagonists, beta 2 stimulants, Th 2 cytokine inhibitors, theophylline, or oral sodium cromoglycate within 72 hours before the oral food challenge tests.
Patients who received oral or intravenous steroids within 2 weeks before undergoing the oral food challenge tests.
Patients that the doctor assessed as being ineligible for other reasons.
200
1st name | Teruaki |
Middle name | |
Last name | Matsui |
Aichi Children's Health and Medical Center
Department of Allergy
474-8710
7-426, Morioka, Obu, Aichi 474-8710, Japan
0562-43-0500
teruaki_matsui@sk00106.achmc.pref.aichi.jp
1st name | Teruaki |
Middle name | |
Last name | Matsui |
Aichi Children's Health and Medical Center
Department of Allergy
474-8710
7-426, Morioka, Obu, Aichi 474-8710, Japan
0562-43-0500
teruaki_matsui@sk00106.achmc.pref.aichi.jp
Aichi Children's Health and Medical Center
Japanese Society of Pediatric Allergy and Clinical Immunology
Other
Institutional Review Board of Aichi Children's Health and Medical Center
7-426, Morioka, Obu, Aichi 474-8710, Japan
0562430500
jigyo@sk00106.achmc.pref.aichi.jp
NO
2018 | Year | 05 | Month | 20 | Day |
Published
https://onlinelibrary.wiley.com/doi/10.1111/all.15451
103
Completed
2018 | Year | 03 | Month | 16 | Day |
2018 | Year | 03 | Month | 16 | Day |
2018 | Year | 05 | Month | 20 | Day |
2022 | Year | 03 | Month | 31 | Day |
2018 | Year | 05 | Month | 20 | Day |
2022 | Year | 08 | Month | 11 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037231
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