Unique ID issued by UMIN | UMIN000032672 |
---|---|
Receipt number | R000037255 |
Scientific Title | One-week hypofractionated radiotherapy in elderly and frail patients with newly diagnosed glioblastoma |
Date of disclosure of the study information | 2018/08/01 |
Last modified on | 2019/01/04 16:07:50 |
One-week hypofractionated radiotherapy in elderly and frail patients with newly diagnosed glioblastoma
One-week hypofractionated radiotherapy in elderly and frail patients with newly diagnosed glioblastoma
One-week hypofractionated radiotherapy in elderly and frail patients with newly diagnosed glioblastoma
One-week hypofractionated radiotherapy in elderly and frail patients with newly diagnosed glioblastoma
Japan |
Glioblastoma
Neurosurgery |
Malignancy
NO
To evaluate the efficacy of one-week hypofractionated radiotherapy in elderly and frail patients with newly diagnosed glioblastoma
Safety
Exploratory
Progression free survival
Overall survival, Response rate, Adverse event, Severe adverse event, Cognitive function, Quality of life
Interventional
Single arm
Non-randomized
Open -no one is blinded
Historical
1
Treatment
Other |
Radiotherapy (Focal 25Gy/5fraction)
65 | years-old | <= |
Not applicable |
Male and Female
1. Newly diagnosed and histologically confirmed glioblastoma (GBM, WHO GradeIV).
2. Registration should be completed >=7days and <=21days after resection or biopsy. The protcol treatment should start>=7days and <=28days after resection or biopsy.
3. Age >=65 years, <=75 years with performance status 3. Age >=76 years with performance status 2 or 3.
4. Regardless of use of GLIADEL Wafer
5. Patient has not received prior chemotherapy or radiotherapy.
6. Written informed consent.
1. Infectious disease requiring systemic treatment.
2. Other active malignancy.
3. Dissemination.
4. Attending physician has determined unsuitable to participate in the study.
40
1st name | |
Middle name | |
Last name | Yohei Miyake |
Yokohama city university
Department of Neurosurgery
3-9, fukuura, kanazawa-ku, yokohama, kanagawa
045-787-2800
ymiyaken@gmail.com
1st name | |
Middle name | |
Last name | Yohei Miyake |
Yokohama city university
Department of Neurosurgery
3-9, fukuura, kanazawa-ku, yokohama, kanagawa
045-787-2800
ymiyaken@gmail.com
Yokohama city university
Yokohama city university
Self funding
NO
2018 | Year | 08 | Month | 01 | Day |
Unpublished
Terminated
2018 | Year | 05 | Month | 22 | Day |
2018 | Year | 08 | Month | 15 | Day |
2018 | Year | 05 | Month | 22 | Day |
2019 | Year | 01 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037255
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |