Unique ID issued by UMIN | UMIN000032948 |
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Receipt number | R000037554 |
Scientific Title | muscle afferent block (MAB) therapy for upper and lower limb spasticity |
Date of disclosure of the study information | 2018/06/11 |
Last modified on | 2023/07/25 06:21:49 |
muscle afferent block (MAB) therapy for upper and lower limb spasticity
muscle afferent block (MAB) therapy for upper and lower limb spasticity
muscle afferent block (MAB) therapy for upper and lower limb spasticity
muscle afferent block (MAB) therapy for upper and lower limb spasticity
Japan |
upper and lower limb spasticity
Neurology | Rehabilitation medicine |
Others
NO
In order to study the most effective administration region for the treatment, muscle afferent block therapy was administered to spasticity after strokes. Subjective symptoms and objective symptoms before and after MAB therapy were evaluated and compared after proximal and distal administration.
Efficacy
Confirmatory
Pragmatic
Subjective symptoms
Changes in subjective symptoms are determined by VAS before and after treatment.
Objective symptoms
The change in objective symptoms is judged by mVAS.
Counts dropout rate after registration.
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Dose comparison
2
Treatment
Medicine | Maneuver |
MAB therapy and evaluation
A. From the proximal muscle group
1.Pre-treatment video shooting, visual analog scale (VAS) evaluation
2.
MAB therapy for the tibialis posterior muscle, and the flexor digitorum superficialis muscle
3.Video shooting after treatment, VAS evaluation
4.MAB therapy for flexor digitorum brevis muscle, opponence muscle
5.Video shooting after treatment, VAS evaluation
B. From the distal muscle group
1.Pre-treatment video shooting, VAS evaluation
2.MAB therapy for short finger flexor muscle, thumb substitute muscle
3.Motion picture shooting after treatment, VAS evaluation
4.MAB therapy for the posterior tibialis muscle, the superficial flexor muscle
5.Movie shooting after treatment, VAS evaluation
16 | years-old | <= |
99 | years-old | >= |
Male and Female
1) Cases with spasm of upper and lower limbs due to sequela such as stroke
2) 2) About participation in the study Case in which consent was obtained from the patient himself in writing
3) 3) Patients over the age of 16
1) under 15 years old
2) those with severe kidney failure or liver failure
3) Pregnant women and women of reproductive age who have not taken effective measures for contraception
4) Others judged to be unsuitable for this research
1000
1st name | shinichi |
Middle name | |
Last name | matsumoto |
Osaka Neurological Institute
Department of Neurology
5610836
2-6-23, Shounai Takaramachi, Toyonaka, Osaka
06-6333-0080
dyt1mc@yahoo.co.jp
1st name | shinichi |
Middle name | |
Last name | matsumoto |
Osaka Neurological Institute
Department of Neurology
561-0836
2-6-23, Shounai Takaramachi, Toyonaka, Osaka
06-6333-0080
dyt1mc@yahoo.co.jp
Department of Neurology, Osaka Neurological Institute,
2-6-23, Shounai Takaramachi, Toyonaka 561-0836, Japan
Department of Neurology, Osaka Neurological Institute,
2-6-23, Shounai Takaramachi, Toyonaka 561-0836, Japan
Self funding
Osaka neurological institute / IRB
2-6-23, Shounai Takaramachi, Toyonaka 561-0836, Japan
06-6333-0080
dyt100mc@yahoo.co.jp
NO
2018 | Year | 06 | Month | 11 | Day |
https://center6.umin.ac.jp/cgi-bin/icdr/ctr_up_reg_f5.cgi
Unpublished
https://center6.umin.ac.jp/cgi-bin/icdr/ctr_up_reg_f5.cgi
1000
duaring the clinical trial
2023 | Year | 07 | Month | 25 | Day |
Patients with spasticity of the upper and lower limbs who visited our hospital
Patients with upper and lower extremity spasticity who wish to participate in the trial.
No adverse events so far
Modified visual analog scale
Enrolling by invitation
2018 | Year | 03 | Month | 30 | Day |
2018 | Year | 03 | Month | 30 | Day |
2018 | Year | 04 | Month | 01 | Day |
2022 | Year | 04 | Month | 01 | Day |
2018 | Year | 06 | Month | 11 | Day |
2023 | Year | 07 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037554
Research Plan | |
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Registered date | File name |
Research case data | |
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