Unique ID issued by UMIN | UMIN000033023 |
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Receipt number | R000037646 |
Scientific Title | Portal hemodynamic effects of lenvatinib in patients with advanced hepatocellular carcinoma: a prospective cohort study |
Date of disclosure of the study information | 2018/06/17 |
Last modified on | 2018/11/21 15:33:59 |
Portal hemodynamic effects of lenvatinib in patients with advanced hepatocellular carcinoma: a prospective cohort study
Portal hemodynamic effects of lenvatinib
Portal hemodynamic effects of lenvatinib in patients with advanced hepatocellular carcinoma: a prospective cohort study
Portal hemodynamic effects of lenvatinib
Japan |
patients with advanced hepatocellular carcinoma
Hepato-biliary-pancreatic medicine |
Malignancy
NO
Evaluation of the portal hemodynamic effect of lenvatinib in patients with advanced HCC
Safety,Efficacy
Changes in portal venous area
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Lenvatinib 12mg per day for 2 weeks (BW >60)
Lenvatinib 8mg per day for 2 weeks (BW <60)
20 | years-old | <= |
Not applicable |
Male and Female
1) Advanced-stage HCC is confirmed by clinical analysis.
2) BCLC stage B2 or B3
1)Tumor invasion in intrahepatic large vessels (Vp4)
2)hepatic encephalopathy, refractory ascites
3)hypertension (160/100 or higher.)
4)Severe renal function(eGFR<50ml/min)
50
1st name | |
Middle name | |
Last name | Hisashi Hidaka |
Kitasato University School of Medicine
Department of Gastroenterology, Internal Medicine
1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0380, Japan
+81-42-778-7750
hisashi7@kitasato-u.ac.jp
1st name | |
Middle name | |
Last name | Haruki Uojima |
Kitasato University School of Medicine
Department of Gastroenterology, Internal Medicine
1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0380, Japan
+81-42-778-7750
kiruha@kitasato-u.ac.jp
Kitasato University School of Medicine
None
Self funding
NO
2018 | Year | 06 | Month | 17 | Day |
Unpublished
Open public recruiting
2018 | Year | 05 | Month | 02 | Day |
2018 | Year | 06 | Month | 12 | Day |
2018 | Year | 06 | Month | 16 | Day |
2018 | Year | 11 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000037646
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