Unique ID issued by UMIN | UMIN000033558 |
---|---|
Receipt number | R000038271 |
Scientific Title | A Clinical study regarding the changing rate of the bone strength of patients with hormone-sensitive breast cancer under the postoperative endocrine therapy |
Date of disclosure of the study information | 2018/09/01 |
Last modified on | 2023/02/02 10:19:22 |
A Clinical study regarding the changing rate of the bone strength of patients with hormone-sensitive breast cancer under the postoperative endocrine therapy
The analysis of the bone strength under the postoperative endocrine therapy of breast cancer
A Clinical study regarding the changing rate of the bone strength of patients with hormone-sensitive breast cancer under the postoperative endocrine therapy
The analysis of the bone strength under the postoperative endocrine therapy of breast cancer
Japan |
breast cancer
Breast surgery |
Malignancy
NO
To analysis the effect to the bone strength of the postoperative endocrine therapy of patients with stage 1-3A hormone-sensitive breast cancer by using an ultrasonic bone measurement system, LD-100
Others
The observation of changing rate
Changing rate for 12 months after starting the postoperative endocrine therapy in following four items derived by an ultrasonic bone measurement system, LD-100
Thickness of distal end of radius
Thickness of cortical bone of radius
Bone mineral density(BMD) of cancellous bone of radius
Elasticity of cancellous bone of radius
1) Changing rate in the BMD for the lumbar vertebrae (L1-L4) on DXA
2) Changes in bone metabolism marker and the other date of blood
3) Relation between the bone strength and the activity, BMI and the clinical data
4) Appearance of morbid fracture within the period of this study
5) Efficacy of irisin, plasmalogen and etc as a biomarker and the relation between them and the activity, BMI and the clinical data
6) Stratified analysis of 1)-5)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Prevention
Device,equipment |
measure the distal end of radius by LD-100
20 | years-old | <= |
85 | years-old | >= |
Female
1) Patients diagnosed with stage 1-3A hormone-sensitive breast cancer and start the postoperative endocrine therapy within the period of this study
2) Estrogen receptor or progesterone receptor positive patients on immunohistochemical staining
3) Those from whom written informed consent regarding this study participation was obtained
1)those can not attend University Hospital, Kyoto Prefectural University of Medicine
2)those are considered to be ineligible by the chief investigator
150
1st name | Tetsuya |
Middle name | |
Last name | Taguchi |
Kyoto Prefectural Univercity of Medicine
Department of Endocrine and Breast Surgery
602-8566
465 kajii-cho Kawaramachi Hirokoji kamigyouku Kyoto Japan
0752515534
ttaguchi@koto.kpu-m.ac.jp
1st name | Satomi |
Middle name | |
Last name | Tomida |
Kyoto Prefectural Univercity of Medicine
Department of Endocrine and Breast Surgery
602-8566
465 kajii-cho Kawaramachi Hirokoji kamigyouku Kyoto Japan
0752515534
satomida@koto.kpu-m.ac.jp
Department of Endocrine and Breast Surgery,Kyoto Prefectural Univercity of Medicine
Kyoto Prefectural Univercity of Medicine
Self funding
Department of Endocrine and Breast Surgery,Kyoto Prefectural Univercity of Medicine
465 kajii-cho Kawaramachi Hirokoji kamigyouku Kyoto Japan
075-251-5111
soumu@koto.kpu-m.ac.jp
NO
2018 | Year | 09 | Month | 01 | Day |
Unpublished
83
Terminated
2018 | Year | 09 | Month | 01 | Day |
2018 | Year | 10 | Month | 03 | Day |
2019 | Year | 02 | Month | 01 | Day |
2023 | Year | 03 | Month | 31 | Day |
2018 | Year | 07 | Month | 30 | Day |
2023 | Year | 02 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000038271
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |