Unique ID issued by UMIN | UMIN000033640 |
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Receipt number | R000038359 |
Scientific Title | Effect of inhalation of hot humidified air on nasal environment |
Date of disclosure of the study information | 2018/08/06 |
Last modified on | 2019/04/02 12:23:35 |
Effect of inhalation of hot humidified air on nasal environment
Effect of inhalation of hot humidified air on nasal environment
Effect of inhalation of hot humidified air on nasal environment
Effect of inhalation of hot humidified air on nasal environment
Japan |
Healthy adults
Oto-rhino-laryngology | Adult |
Others
NO
To investigate the effect of low temperature and humidity, and heated humidification on nasal environment.
Efficacy
Exploratory
Indicator of nasal function; rhinomanometry and saccharin clearance time
Condition of nose; temperature and humidity in nasal cavity, rheology characteristics of nasal mucus, and the amount of bacteria
Interventional
Cross-over
Randomized
Individual
Single blind -investigator(s) and assessor(s) are blinded
Dose comparison
Institution is not considered as adjustment factor.
Numbered container method
6
Treatment
Other |
After exposure to 20C, 40% RH for 120 minutes, subjects use test product A. With a washout period for more than one week between the crossover, subjects use test product B after exposure to 20C, 40% RH for 120 minutes. With a washout period for more than one week between the crossover, subjects use test product C after exposure to 20C, 40% RH for 120 minutes.
After exposure to 20C, 40% RH for 120 minutes, subjects use test product A. With a washout period for more than one week between the crossover, subjects use test product C after exposure to 20C, 40% RH for 120 minutes. With a washout period for more than one week between the crossover, subjects use test product B after exposure to 20C, 40% RH for 120 minutes.
After exposure to 20C, 40% RH for 120 minutes, subjects use test product B. With a washout period for more than one week between the crossover, subjects use test product A after exposure to 20C, 40% RH for 120 minutes. With a washout period for more than one week between the crossover, subjects use test product C after exposure to 20C, 40% RH for 120 minutes.
After exposure to 20C, 40% RH for 120 minutes, subjects use test product B. With a washout period for more than one week between the crossover, subjects use test product C after exposure to 20C, 40% RH for 120 minutes. With a washout period for more than one week between the crossover, subjects use test product A after exposure to 20C, 40% RH for 120 minutes.
After exposure to 20C, 40% RH for 120 minutes, subjects use test product C. With a washout period for more than one week between the crossover, subjects use test product A after exposure to 20C, 40% RH for 120 minutes. With a washout period for more than one week between the crossover, subjects use test product B after exposure to 20C, 40% RH for 120 minutes.
After exposure to 20C, 40% RH for 120 minutes, subjects use test product C. With a washout period for more than one week between the crossover, subjects use test product B after exposure to 20C, 40% RH for 120 minutes. With a washout period for more than one week between the crossover, subjects use test product A after exposure to 20C, 40% RH for 120 minutes.
20 | years-old | <= |
59 | years-old | >= |
Male
1.Informed consent provided
2.Able to follow the instruction of the study team
1.Subjects with skin diseases at nose
2.Subjects with chronic illness related to nose
3.Subjects who have skin allergy to drugs, cosmetics, masks, and temperature
4.Subjects who participate in other research or treatment with physical loads that affect this test
5.Claustrophobic subjects
6.Subjects deemed inappropriate to participate in this study by the principle investigator
20
1st name | |
Middle name | |
Last name | Takuya Mori |
Kao Corporation
Biological Science Research
2606, Akabane, Ichikai-machi, haga-gun, Tochigi, 321-3497, JAPAN
+81-285-68-7769
mori.takuya@kao.com
1st name | |
Middle name | |
Last name | Yui Hirama |
Kao Corporation
Biological Science Research
2606, Akabane, Ichikai-machi, haga-gun, Tochigi, 321-3497, JAPAN
+81-285-68-7828
hirama.yui2@kao.com
Kao Corporation
Kao Corporation
Profit organization
NO
花王株式会社(栃木県)
2018 | Year | 08 | Month | 06 | Day |
Unpublished
Completed
2018 | Year | 07 | Month | 18 | Day |
2018 | Year | 07 | Month | 18 | Day |
2018 | Year | 08 | Month | 07 | Day |
2019 | Year | 03 | Month | 10 | Day |
2018 | Year | 08 | Month | 06 | Day |
2019 | Year | 04 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000038359
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