Unique ID issued by UMIN | UMIN000033688 |
---|---|
Receipt number | R000038408 |
Scientific Title | Retrospective observational study on adjuvant chemotherapy after advanced lower rectal cancer surgery |
Date of disclosure of the study information | 2018/08/09 |
Last modified on | 2020/08/13 23:10:33 |
Retrospective observational study on adjuvant chemotherapy after advanced lower rectal cancer surgery
Retrospective observational study on adjuvant chemotherapy after advanced lower rectal cancer surgery
Retrospective observational study on adjuvant chemotherapy after advanced lower rectal cancer surgery
Retrospective observational study on adjuvant chemotherapy after advanced lower rectal cancer surgery
Japan |
Advanced rectal cancer
Gastrointestinal surgery |
Malignancy
NO
To investigate the proportion and efficacy of adjuvant chemotherapy after advanced lower rectal cancer surgery
Efficacy
Implementation rate of adjuvant chemotherapy
1)Regimen, period of administration, total dose of adjuvant chemotherapy
2)Adverse event of adjuvant chemotherapy
3)Reasons for not performingen adjuvant chemotherapy after surgery
4)Relapse-free survival, overall survival, local recurrence rate
5)Risk factors for local recurrence
6)Risk factors for anastomatic leakage
7)Risk factors for postoperative urinary disorder
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1)Patient who underwnet rectal cancer surgery between 2008 and 2012
2)Tumor distal edge was located below peritoneal reflection
3)Pathological T3/T4 or N1/N2/N3
4)No distant metastasis
1)Patient who performed preoperative treatment (chemotherapy, radiotherapy, chemoradiotherapy)
2)Petients who are considered to be inappropriate for this trial by doctor
1000
1st name | Mitsuyoshi |
Middle name | |
Last name | Ota |
Yokohama City University Medical Center
Department of Surgery, Gastroenterological Center
2320024
4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Japan
045-261-5656
m_ota@yokohama-cu.ac.jp
1st name | Kazuya |
Middle name | |
Last name | Nakagawa |
Yokohama City University Medical Center
Department of Surgery, Gastroenterological Center
2320024
4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Japan
045-261-5656
nakagawakazuya0827@yahoo.co.jp
Yokohama City University Medical Center
Yokohama Clinical Oncology Group (YCOG)
Self funding
Ethics committee of Yokohama City University
3-9 Fukuura, Kanazawa-Ku, Yokohama
045-370-7627
nextjim1@yokohama-cu.ac.jp
NO
横浜市立大学附属病院(神奈川県)、横浜市立市民病院(神奈川県)、横浜市南部病院(神奈川県)、横浜市立みなと赤十字病院(神奈川県)、横浜医療センター(神奈川県)、保土ヶ谷中央病院(神奈川県)、えきさい会病院(神奈川県)、若草病院(神奈川県)、横須賀共済病院(神奈川県)、横須賀市立市民病院(神奈川県)、藤沢市民病院(神奈川県)、NTT東日本関東病院(東京都)、伊東市民病院(静岡県)
2018 | Year | 08 | Month | 09 | Day |
None
Unpublished
None
845
Of 811 patients, 401 patients (49.4%) received adjuvant chemotherapy after surgery.
2020 | Year | 08 | Month | 13 | Day |
Of 811 patients, 530 patients were male and 281 were female. The median age of the patients was 67 years. Pathological stage was pStage II in 341 patitents and pStage III in 470 patients.
Medical reports from 845 patients were collected from 13 hospitals. Of these, 34 were excluded from the analysis because radical resection could not complete. The remaining 811 patients were analyzed.
None
rate of adjuvant chemotherapy
Completed
2015 | Year | 05 | Month | 29 | Day |
2015 | Year | 08 | Month | 01 | Day |
2015 | Year | 10 | Month | 01 | Day |
2017 | Year | 12 | Month | 31 | Day |
To investigate the proportion and efficacy of adjuvant chemotherapy after advanced lower rectal cancer surgery
2018 | Year | 08 | Month | 08 | Day |
2020 | Year | 08 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000038408
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