Unique ID issued by UMIN | UMIN000033833 |
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Receipt number | R000038497 |
Scientific Title | Whether hybrid training during dialysis improve patient's physical function and inflammation and arteriosclerosis |
Date of disclosure of the study information | 2018/08/29 |
Last modified on | 2018/08/21 12:28:24 |
Whether hybrid training during dialysis improve patient's physical function and inflammation and arteriosclerosis
Carnitine deficiency is associated with decreased exercise activity in hemodialysis patients
Whether hybrid training during dialysis improve patient's physical function and inflammation and arteriosclerosis
Carnitine deficiency is associated with decreased exercise activity in hemodialysis patients
Japan |
hemodyalysis people
Nephrology |
Others
NO
Carnitine deficiency is common in hemodialysis patients and is associated with muscle atrophy in hemodialysis patients. Here we investigated whether carnitine levels could be one of the independent predictor for exercise capacity in these patients
Safety,Efficacy
Exercise tolerance test
Before exercise and after 3 months Grip strength time up Go test Lower limb muscle strength functional reach test Body composition measurement Thigh muscle area by MRI etc
Interventional
Parallel
Non-randomized
Open -but assessor(s) are blinded
Placebo
3
Treatment
Medicine |
We administer to the patient levocarnitine 1000 mg/dose during every dialysis for 3 months and compare with the placebo group.
We administer to the patient levocarnitine 1000 mg/dose during every dialysis for 3 months and compare it with the exercise group.
We administer to the patient levocarnitine 1000 mg/dose during every dialysis for 3 months and compare with the hybrid exercise group.
20 | years-old | <= |
90 | years-old | >= |
Male and Female
1.Patients over the age of 20 years with end stage renal disease undergoing hemodialysis
2.Patients able to provide written informed consent for study participation
1.Patients under the age of 20 years old
2.Patients who are contraindicated in the package insert of Levocarnitine
3.Patients undergoing combination therapy with peritoneal dialysis and hemodialysis
4.Pregnant woman, or a woman who have possibility of pregnancy
5.Others not inadequate judged by a physician
6.Patients who do not obtain consent
40
1st name | |
Middle name | |
Last name | kei Fukami |
Kurume univercity
nephrology division
asahimachi kurumecity fukuokapurifacture
0942-31-7002
fukami@med.kurume-u.ac.jp
1st name | |
Middle name | |
Last name | Junko Yano |
Kurume University
Division of Nephrology, Department on Medicine
67 Asahi-machi, Kurume-shi, Fukuoka, Japan
0942-31-7002
yano_junko@med.kurume-u.ac.jp
Division of Nephrology, Department on Medicine, Kurume University
Division of Nephrology, Department on Medicine, Kurume University
Other
NO
2018 | Year | 08 | Month | 29 | Day |
Unpublished
Completed
2015 | Year | 04 | Month | 01 | Day |
2016 | Year | 04 | Month | 01 | Day |
2018 | Year | 04 | Month | 01 | Day |
2018 | Year | 08 | Month | 21 | Day |
2018 | Year | 08 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000038497
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