Unique ID issued by UMIN | UMIN000033835 |
---|---|
Receipt number | R000038589 |
Scientific Title | Clinical characteristics of papillary thyroid carcinoma patients with Delphian lymph node metastasis: a single-institution study, systemic review and meta-analysis |
Date of disclosure of the study information | 2018/08/21 |
Last modified on | 2018/08/21 13:37:33 |
Clinical characteristics of papillary thyroid carcinoma patients with Delphian lymph node metastasis: a single-institution study, systemic review and meta-analysis
Predicting spread to lymph nodes in papillary thyroid cancer patients based on clinical characteristics
Clinical characteristics of papillary thyroid carcinoma patients with Delphian lymph node metastasis: a single-institution study, systemic review and meta-analysis
Predicting spread to lymph nodes in papillary thyroid cancer patients based on clinical characteristics
Asia(except Japan) |
thyroid carcinoma and Delphian lymph node metastasis
Endocrinology and Metabolism | Endocrine surgery | Adult |
Malignancy
NO
The aim of this study is to evaluate the clinicopathological characteristics of papillary thyroid carcinoma patients with Delphian lymph node metastasis
Others
To identify the independent risk factors for Delphian lymph node metastasis and the ability of Delphian lymph node metastasis to predict further central lymph node metastasis and lateral lymph node metastasis
Exploratory
Explanatory
Not applicable
Clinical characteristics of Delphian lymph node metastasis in thyroid carcinoma was evaluated from 2017 to 2018.
Independent risk factors for DLN metastasis, assessed through multivariate analysis of significant factors.
Ability of DLN metastasis to predict further central lymph node metastasis and lateral lymph node metastasis, assessed through reviewing central and lateral lymph node metastasis
Observational
18 | years-old | <= |
70 | years-old | > |
Male and Female
1. Total thyroidectomy or ipsilateral thyroidectomy with central lymph node dissection
2. Aged 18-70
3. Preoperatively diagnosed with micropapillary carcinoma, based on ultrasound-guided fine needle aspiration cytology
4. Signed informed consent
1. Contraindications for anaesthesia (e.g. pregnancy, multiple organ failure, mental illness)
2. History of neck surgery or radiotherapy
3. Inability to comply with follow-up protocol
146
1st name | |
Middle name | |
Last name | Ming Qiu |
Changzheng Hospital affliated Second Military Medical University
Shanghai
No. 415 in Fengyang Road in Huangpu District
86-21-81885801
qium127@smmu.edu.cn
1st name | |
Middle name | |
Last name | Ming Qiu |
Changzheng Hospital affliated Second Military Medical University
Shanghai
No. 415 in Fengyang Road in Huangpu District
86-21-81885801
qium127@smmu.edu.cn
Changzheng Hospital
General surgery department
the National Natural Science Foundation of China
Outside Japan
China
none
none
NO
Changzheng Hospital affliated Second Military Medical University
2018 | Year | 08 | Month | 21 | Day |
Unpublished
In own series, Delphian lymph node metastasis was detected in 12 (8.2%) of 146 papillary thyroid carcinoma patients and was significantly associated with tumor size >1cm (P=0.029) and extrathyroid extension (P=0.002) in the multivariate analysis. Delphian lymph node metastasis was highly predictive of further central lymph node metastasis (positive predictive value=91.7%, netative predictive value=67.9%) and moderately predictive of lateral lymph node metastasis (positive predictive value=25.0%, negative predictive value=95.5%).
No longer recruiting
2017 | Year | 06 | Month | 21 | Day |
2017 | Year | 07 | Month | 01 | Day |
2018 | Year | 05 | Month | 31 | Day |
2018 | Year | 05 | Month | 31 | Day |
2018 | Year | 05 | Month | 31 | Day |
2018 | Year | 06 | Month | 22 | Day |
none
2018 | Year | 08 | Month | 21 | Day |
2018 | Year | 08 | Month | 21 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000038589