Unique ID issued by UMIN | UMIN000034007 |
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Receipt number | R000038777 |
Scientific Title | Corticospinal excitability affected by conflicting visual and proprioceptive information |
Date of disclosure of the study information | 2018/09/05 |
Last modified on | 2020/09/06 06:28:57 |
Corticospinal excitability affected by conflicting visual and proprioceptive information
Corticospinal excitability affected by conflicting multisensory information
Corticospinal excitability affected by conflicting visual and proprioceptive information
Corticospinal excitability affected by conflicting multisensory information
Japan |
healthy and neurologically intact
adults
Adult |
Others
NO
The aim of this study is to determine whether conflicting visual and proprioceptive information affects the corticospinal excitability and kinesthesia.
Others
This study investigates change in motor evoked potentials by visual and vibratory stimulations.
Motor evoked potentials of the flexor and extensor carpi radialis muscles are recorded during vibratory stimulation over the extensor carpi radialis muscle. In addition, illusory percept of flexion movement is also assessed during vibratory stimulation.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Treatment
Device,equipment |
Subjects were seated wirh their hands and forearms resting on a pillow on the desk. For 25 scalp position, 5 transcranial magnetic stimulation of 120 percent of the resting motor threshold is delivered to compute center of gravity (hot spot in M1) of the flexor and extensor carpi radialis muscles. Then, subjects observe a hand action depicted on a computer screen during vibratory stimulation over the extensor carpi radialis muscle (amplitude 1.0 mm, frequency 80 Hz cycle duration of 5 min: 10s on, 52 off). In addition, 60 transcranial magnetic stimulation of 120 percent of the extensor carpi radialis muscle's resting motor threshold is delivered at the midpoint between the center of gravities of the flexor and extensor carpi radialis muscles (interstimulus interval: 10 s) during vibratory stimulation.
20 | years-old | <= |
50 | years-old | >= |
Male and Female
The subjects are healthy, neurologically intact, right handed volunteers. In addition, screening shows that none are at risk for adverse events during transcranial magnetic stimulation.
None
20
1st name | Takako |
Middle name | |
Last name | Suzuki |
Saitama Prifectual University
School of Health Sciences
3438540
820 Sannomiya, Koshigaya City, Saitama
048-973-4125
suzuki-takako@spu.ac.jp
1st name | Takako |
Middle name | |
Last name | Suzuki |
Saitama Prefectural University
School of Health Sciences
3438540
820 Sannomiya, Koshigaya City, Saitama
048-973-4125
suzuki-takako@spu.ac.jp
Saitama Prefectural University
Japan Society for the Promotion of Science
Japanese Governmental office
Ethics Committee of the Saitama Prefectural Univercity
820 Sannomiya, Koshigaya City Saitama
048-971-0500
shorei@spu.ac.jp
NO
2018 | Year | 09 | Month | 05 | Day |
https://www.frontiersin.org/articles/10.3389/fnint.2019.00063/full
Published
https://www.frontiersin.org/articles/10.3389/fnint.2019.00063/full
20
The ECR motor evoked potential (MEP) amplitudes significantly increased in the control condition compared to the resting condition (p<0.0001), whereas the FCR MEP amplitudes did not change between the resting and control conditions. The ECR MEP amplitudes significantly increased in the static condition compared to the dynamic condition (p<0.0001)
. On the other hand, the FCR MEP amplitudes significantly increased in the dynamic condition compared to the static condition (p<0.0001).
2020 | Year | 09 | Month | 06 | Day |
No participant had risks of adverse events from TMS or use of medications or any psychiatric or neurological diseases.
Subjects who voluntarily participated in the public offering were asked to provide oral and written informed consent.
None
Motor evoked potentials of the flexor and extensor carpi radialis muscles were recorded immediately after stimulated by vibratory or movie observation over the 4 experiment's conditions.
Completed
2018 | Year | 07 | Month | 01 | Day |
2017 | Year | 11 | Month | 30 | Day |
2018 | Year | 09 | Month | 05 | Day |
2019 | Year | 03 | Month | 15 | Day |
2018 | Year | 09 | Month | 03 | Day |
2020 | Year | 09 | Month | 06 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000038777
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