Unique ID issued by UMIN | UMIN000034555 |
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Receipt number | R000039392 |
Scientific Title | Berberine containing therapy for Helicobacter Pylori treatment among patients with previous failed eradication |
Date of disclosure of the study information | 2018/10/20 |
Last modified on | 2019/12/29 16:35:35 |
Berberine containing therapy for Helicobacter Pylori treatment among patients with previous failed eradication
Berberine containing therapy for patients with previous failed helicobacter pylori eradication
Berberine containing therapy for Helicobacter Pylori treatment among patients with previous failed eradication
Berberine containing therapy for patients with previous failed helicobacter pylori eradication
Asia(except Japan) |
H. pylori infection
Gastroenterology |
Others
NO
To compare the therapy efficacy (eradication rate) and safety between Bismuth Containing Quadruple Therapy (BCQT) and Berberine Containing Therapy (BCQT plus berberine)
Efficacy
eradication rate of H. pylori
Interventional
Parallel
Randomized
Individual
Single blind -participants are blinded
Active
2
Treatment
Medicine |
Berberine Containing Therapy (Berberine 0.3g tid, Rabeprazole 10mg bid, Bismuth 500mg bid, Amoxicillin 1g bid and Minocycline 1000mg bid) for 14 days
Bismuth Containing Quadruple Therapy (Rabeprazole 10mg bid, Bismuth 500mg bid, Amoxicillin 1g bid and Minocycline 1000mg bid) for 14 days
18 | years-old | <= |
80 | years-old | >= |
Male and Female
Patients positive to Rapid Urease Test
Patients positive to 13C Urease Breath Test
Patients verified of Hp infection with pathology
Patients with previous failed H. pylori eradication
Patients with allergy history of drugs medicated in this trail
Patients with history of hepatic or/and renal dysfunction
Patients with history of operation on upper digestive tract
Patients with alcoholism and drug abuse
Patients in pregnancy or lactation
Patients who ever participated other clinical trials in latest 3 months
90
1st name | Yu |
Middle name | |
Last name | Lan |
Beijing Jishuitan Hospital
Departement of Gastroenterology
100035
No. 31, Xinjiekou East Street, Beijing
86-10-58398289
lanyu-mail@sohu.com
1st name | Xiao-Bei |
Middle name | |
Last name | Si |
Beijing Jishuitan Hospital
Departement of Gastroenterology
100035
No. 31, Xinjiekou East Street, Beijing
86-10-58398289
sixiaobei2008@126.com
Health bureau of Beijing
Administration of traditional Chinese medicine of Beijing
Government offices of other countries
Beijing Jishuitan Hospital
No. 31, Xinjiekou East Street, Beijing
86-10-58398289
sixiaobei2008@126.com
NO
2018 | Year | 10 | Month | 20 | Day |
Partially published
Open public recruiting
2018 | Year | 09 | Month | 01 | Day |
2018 | Year | 09 | Month | 10 | Day |
2018 | Year | 09 | Month | 01 | Day |
2019 | Year | 12 | Month | 20 | Day |
2018 | Year | 10 | Month | 17 | Day |
2019 | Year | 12 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000039392
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