Unique ID issued by UMIN | UMIN000034893 |
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Receipt number | R000039781 |
Scientific Title | Analysis of refractory ascites components of patients with ovarian cancer, fallopian tube cancer and peritoneal cancer, and examination of influence by Cell-free and Concentrated Ascites Reinfusion Therapy (CART) |
Date of disclosure of the study information | 2018/11/19 |
Last modified on | 2020/11/20 14:13:21 |
Analysis of refractory ascites components of patients with ovarian cancer, fallopian tube cancer and peritoneal cancer, and examination of influence by Cell-free and Concentrated Ascites Reinfusion Therapy (CART)
Analysis of ascites components, and examination of influence by CART
Analysis of refractory ascites components of patients with ovarian cancer, fallopian tube cancer and peritoneal cancer, and examination of influence by Cell-free and Concentrated Ascites Reinfusion Therapy (CART)
Analysis of ascites components, and examination of influence by CART
Japan |
ovarian cancer, fallopian tube cancer and peritoneal cancer
Obstetrics and Gynecology |
Malignancy
NO
To investigate cytokines levels in serum and ascites, QOL, and safety of pre-post CART in patients complicating refractory ascites with ovarian cancer, fallopian tube cancer, and peritoneal cancer.
Others
Cytokine profile of ascites, ascites after filtration and concentration, and serum.
Exploratory
Others
Not applicable
Cytokine profile of ascites, ascites after filtration and concentration, and serum.
A) Evaluation of QOL in pre-post CART
B) Changes in cytokine levels of ascites filtered and concentrated ascites in storage at 4 degrees
C) Blood test values of pre-post CART
D) Adverse events
Observational
20 | years-old | <= |
80 | years-old | > |
Male and Female
1. Patients complicating refractory ascites with ovarian cancer, fallopian tube cancer and peritoneal cancer patients
2. Patients who are possible to puncture ascites
3. Patients who agree with the informed consent form
4. Patients aged from 20 to 79 years old at the time of obtaining informed consent
5. Patients who are necessary of CART
1. Patients with fever and suspected of detecting endotoxin
2. Highly immunocompromised patients such as bone marrow transplantation
3. Patients with severe heart failure, renal failure, liver failure combined
4. Patients complicated with bacterial peritonitis
5. Serious liver disorder patients with overt jaundice
6. Patients used Bevacizumab within 6 weeks
7. Patients using steroids for mitigation purposes
8. Patients participating in other trials and clinical studies
9. Patients who are determined to be disqualified by a principal investigator
15
1st name | Hiroaki |
Middle name | |
Last name | Itamochi |
Iwate Medical University School of Medicine
Department of Obstetrics and Gynecology
028-3695
2-1-1 Idaidori, Shiwagun Yahabacho, Iwate
019-613-7111
itamochi@iwate-med.ac.jp
1st name | Masahiro |
Middle name | |
Last name | Kagabu |
Iwate Medical University School of Medicine
Department of Obstetrics and Gynecology
028-3695
2-1-1 Idaidori, Shiwagun Yahabacho, Iwate
019-613-7111
mkagabu@iwate-med.ac.jp
Iwate Medical University
ASAHI KASEI MEDICAL CO., LTD.
Profit organization
Japan
Juntendo University
Iwate Medical University
1-1-1 Idaidori, Shiwagun Yahabacho, Iwate
019-651-5111
kenkyu-rinri@j.iwate-med.ac.jp
NO
岩手医科大学附属病院(岩手県)、順天堂大学医学部附属順天堂医院(東京都)
2018 | Year | 11 | Month | 19 | Day |
Unpublished
No longer recruiting
2017 | Year | 12 | Month | 13 | Day |
2017 | Year | 12 | Month | 13 | Day |
2018 | Year | 03 | Month | 14 | Day |
2020 | Year | 12 | Month | 31 | Day |
observational research
2018 | Year | 11 | Month | 14 | Day |
2020 | Year | 11 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000039781
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