Unique ID issued by UMIN | UMIN000035059 |
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Receipt number | R000039867 |
Scientific Title | The differential effects of vestibular simulations between neck flexion and extension on cerebral autoregulation |
Date of disclosure of the study information | 2018/11/28 |
Last modified on | 2021/02/19 10:00:30 |
The differential effects of vestibular simulations between neck flexion and extension on cerebral autoregulation
The differential effects of vestibular simulations between neck flexion and extension on cerebral autoregulation
The differential effects of vestibular simulations between neck flexion and extension on cerebral autoregulation
The differential effects of vestibular simulations between neck flexion and extension on cerebral autoregulation
Japan |
Healthy adult volunteers
Adult |
Others
NO
The purpose is to investigate the differential effects of vestibular simulations between neck flexion and extension on cerebral autoregulation.
Others
physiological changes
Gain, coherence and phase between arterial blood pressure and cerebral blood flow during 6-min neck extension and 6-min neck flexion
Cerebral blood flow velocity, pulsatility index, blood pressure variability, respiratory indexes, intracranial pressure, baroreflex, heart rate variability
Interventional
Cross-over
Randomized
Individual
Open -no one is blinded
No treatment
2
Prevention
Other |
6-min neck flexion in a sitting position
6-min neck extension in a sitting position
20 | years-old | <= |
Not applicable |
Male and Female
Healthy adults consented to participate in the study
Not satisfy selection criteria noted above.
16
1st name | Kenichi |
Middle name | |
Last name | Iwasaki |
Nihon University School of Medicine
Division of Hygiene, Department of Social Medicine
173-8610
30-1, Oyaguchi-Kamicho, Itabashi-ku, Tokyo
03-3972-8111
iwasaki.kenichi@nihon-u.ac.jp
1st name | Tomokazu |
Middle name | |
Last name | Kato |
Nihon University School of Medicine
Division of Hygiene, Department of Social Medicine
173-8610
30-1, Oyaguchi-Kamicho, Itabashi-ku, Tokyo
0339728111
kato.tomokazu@nihon-u.ac.jp
Division of Hygiene, Department of Social Medicine, Nihon University School of Medicine
Japan Society for the Promotion of Science
Japanese Governmental office
Japan
Nihon University School of Medicine
30-1, Oyaguchi-Kamicho, Itabashi, Tokyo
03-3972-8111
med.kenjim@nihon-u.ac.jp
NO
日本大学医学部(東京都)
2018 | Year | 11 | Month | 28 | Day |
https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr.cgi?function=brows&action=brows&recptno=R000039867&ty
Partially published
https://kuleuvencongres.be/icp2019/141-kato-tomokazu-b.pdf
15
Arterial blood pressure (ABP) and cerebral blood flow velocity were measured during neck flexion and extension in the sitting position.
Mean ABP variability in the low frequency range increased significantly during both neck flexion and extension compared with the upright head position; however, no changes in the transfer function gain were seen in that range.
The present results suggest that dynamic cerebral autoregulation may be maintained during neck flexion and extension in healthy adults.
2020 | Year | 04 | Month | 18 | Day |
15 healthy adults, ages 23(2)yr; height 170(4) cm; weight 64(6)kg; mean(SD)
After explanation of this study to candidates by recruitment with the poster, all participants provided written informed consent as well as a medical history regarding circulation and were screened based on a physical examination including electrocardiography and blood pressure measurements. Exclusion criteria comprised failure to obtain CBF velocity signals in the right middle cerebral artery by transcranial Doppler ultrasonography.
None
Arterial blood pressure (ABP)
Cerebral blood flow velocity (CBFV)
Mean ABP variability
Mean CBFV variability
Transfer function gain between mean ABP variability and mean CBFV variability.
Completed
2018 | Year | 09 | Month | 18 | Day |
2018 | Year | 09 | Month | 18 | Day |
2018 | Year | 11 | Month | 28 | Day |
2019 | Year | 03 | Month | 31 | Day |
2020 | Year | 08 | Month | 31 | Day |
2020 | Year | 08 | Month | 31 | Day |
2020 | Year | 08 | Month | 31 | Day |
2018 | Year | 11 | Month | 28 | Day |
2021 | Year | 02 | Month | 19 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000039867
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