Unique ID issued by UMIN | UMIN000034968 |
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Receipt number | R000039873 |
Scientific Title | Effect of radiation according to therapeutic nuclear medicine on DNA |
Date of disclosure of the study information | 2018/11/22 |
Last modified on | 2022/04/27 19:51:18 |
Effect of radiation according to therapeutic nuclear medicine on DNA
Effect of therapeutic nuclear medicine on DNA
Effect of radiation according to therapeutic nuclear medicine on DNA
Effect of therapeutic nuclear medicine on DNA
Japan |
Thyroid cancer
Radiology |
Malignancy
NO
To detect and quantify the DNA damage according to therapeutic nuclear medicine procedures with gamma-H2AX and chromosomal analysis using FISH method. Equality of detection power of DNA damage using gamma-H2AX measuring and chromosomal analysis is also assessed.
Others
Radiation Effect
Exploratory
Pragmatic
Not applicable
Changes of DNA damage between bef
ore I-131 administration and three days after administration.
correlation between DNA damage and blood sample data/history/therapeutic record/I-131 dose/emitted radiation dose from patient.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients who are administered I-131 for therapeutic purpose in isolation room.
Patients who are pregnant or possibly pregnant.
Patients who are performing breast feeding to baby.
90
1st name | Takashi |
Middle name | |
Last name | Kudo |
Nagasaki University
Department of Radioisotope Medicine, Atomic Bomb Disease Institute
8258523
12-4 Sakamoto-1-chome, Nagasaki, Nagasaki
095-819-7101
tkudo123@nagasaki-u.ac.jp
1st name | Takashi |
Middle name | |
Last name | Kudo |
Nagasaki University
Department of Radioisotope Medicine, Atomic Bomb Disease Institute
8528523
12-4 Sakamoto-1-chome, Nagasaki, Nagasaki
095-819-7101
tkudo123@nagasaki-u.ac.jp
Nagasaki University
Nagasaki University
Other
IRB of Nagasaki University Hospital
1-7-1 Sakamoto, Nagasaki, Japan
095-819-7229
gaibushikin@ml.nagasaki-u.ac.jp
NO
2018 | Year | 11 | Month | 22 | Day |
Unpublished
Terminated
2018 | Year | 11 | Month | 19 | Day |
2018 | Year | 11 | Month | 20 | Day |
2018 | Year | 12 | Month | 01 | Day |
2021 | Year | 03 | Month | 31 | Day |
We will acquire DNA damage measurement. Data are not yet achieved.
2018 | Year | 11 | Month | 21 | Day |
2022 | Year | 04 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000039873
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