Unique ID issued by UMIN | UMIN000035078 |
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Receipt number | R000039993 |
Scientific Title | Relationship between anterior chamber protein concentration and surgical outcome in exfoliation glaucoma |
Date of disclosure of the study information | 2019/02/01 |
Last modified on | 2021/12/02 09:29:07 |
Relationship between anterior chamber protein concentration and surgical outcome in exfoliation glaucoma
Anterior chamber protein concentration of exfoliation glaucoma
Relationship between anterior chamber protein concentration and surgical outcome in exfoliation glaucoma
Anterior chamber protein concentration of exfoliation glaucoma
Japan |
glaucoma
Ophthalmology |
Others
NO
Collect anterior chamber water during surgery. By measuring the protein concentration in the anterior chamber water, the relation between the incidence of desquamation glaucoma and the postoperative performance is evaluated.
Others
There is no report comparing desquamation concentrations in the eye of desquamation glaucoma with cases with only desquamation, the rate of transition to glaucoma is unknown. In addition, reports showing that trabeculectomy is effective for desquamation glaucoma in the past have been reported 2) 3), in recent years there have been cases in which intraocular pressure rises in the fifth year after surgery , It is inferred that the desquamation concentration may be involved in postoperative results.
We focused on the concentration of desquamation in the anterior chamber as a factor related to the postoperative outcome of desquamating glaucoma. By collecting the anterior chamber water during surgery and measuring its concentration, the involvement of the incidence of desquamation glaucoma and the association of postoperative results are evaluated and the correlation with other findings is examined.
Confirmatory
Protein concentration in the anterior chamber.IOP.
Visual acuity, endothelial cell density, pupil diameter
Interventional
Parallel
Non-randomized
Open -no one is blinded
Active
NO
NO
Institution is not considered as adjustment factor.
NO
No need to know
3
Treatment
Maneuver |
Cataract surgery group without any cataract disease
Cataract surgery group admitted desquamation but not having glaucoma
Glaucoma surgery group with desquamation glaucoma
20 | years-old | <= |
90 | years-old | > |
Male and Female
A cataract operation group that does not recognize diseases other than cataract, a cataract operation group that admits desquamation but does not develop glaucoma, and a glaucoma operation group that has desquamation glaucoma, and explained the case before operation and consent was obtained
Patients who have disorders other than cataract and glaucoma. Patient who is difficult to collect anterior aqueous humor. Patient with poor fixation.
75
1st name | Nobuyuki |
Middle name | |
Last name | Shoji |
Kitasato university
Ophthalmology
2520329
Kanagawa prefecture Sagamihara-shi Minami-ku Kitasato 1-15-1
0427788464
kos@med.kitasato-u.ac.jp
1st name | Yusuke |
Middle name | |
Last name | Kono |
Kitasato university
Ophthalmology
2520329
Kanagawa prefecture Sagamihara-shi Minami-ku Kitasato 1-15-1
0427788464
yusukeshonan@gmail.com
Kitasato university
Kitasato university
Other
Kitasato university
Kanagawa prefecture Sagamihara-shi Minami-ku Kitasato 1-15-1
0427788464
yusukeshonan@gmail.com
NO
2019 | Year | 02 | Month | 01 | Day |
https://www.kitasato-u.ac.jp/khp/
Unpublished
https://www.kitasato-u.ac.jp/khp/
21
The concentration of glycosaminoglycans in the water was below the detection limit of the test kit and could not be analyzed.
2021 | Year | 12 | Month | 02 | Day |
Glaucoma patients who underwent glaucoma surgery
Recruit from surgical patients
No
IOP, glycosaminoglycan in aqueous humor
Completed
2018 | Year | 08 | Month | 01 | Day |
2018 | Year | 08 | Month | 01 | Day |
2018 | Year | 12 | Month | 01 | Day |
2020 | Year | 03 | Month | 28 | Day |
2020 | Year | 03 | Month | 28 | Day |
2018 | Year | 11 | Month | 30 | Day |
2021 | Year | 12 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000039993
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