Unique ID issued by UMIN | UMIN000035100 |
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Receipt number | R000040011 |
Scientific Title | The Utility and Validity of Intracoronary Administration of Nicorandil Alone for the Measurement of Fractional Flow Reserve in Patients With Intermediate Coronary Stenosis |
Date of disclosure of the study information | 2018/12/01 |
Last modified on | 2020/06/02 22:25:00 |
The Utility and Validity of Intracoronary Administration of Nicorandil Alone for the Measurement of Fractional Flow Reserve in Patients With Intermediate Coronary Stenosis
Intracoronary Nicorandil for the Measurement of Fractional Flow Reserve
The Utility and Validity of Intracoronary Administration of Nicorandil Alone for the Measurement of Fractional Flow Reserve in Patients With Intermediate Coronary Stenosis
Intracoronary Nicorandil for the Measurement of Fractional Flow Reserve
Japan |
Angina Pectoris
Cardiology |
Others
NO
The purpose of this study is to investigate the usefulness and safety of intracoronary nicorandil (ICN) alone compared with intravenous adenosine 5'-triphosphate (IVATP) and ICN during IVATP for the achievement of maximal hyperemia in patients with suspected angina pectoris.
Efficacy
Reliability for FFR value after administration of each drug
The incidence of side effect for each drug
Interventional
Factorial
Non-randomized
Open -no one is blinded
Dose comparison
6
Diagnosis
Medicine |
2mg of intracoronary nicorandil
continuous intravenous infusion of ATP 150microg/kg/min for 2 minutes
continuous intravenous infusion of ATP 210microg/kg/min for 2 minutes
0.5mg of intracoronary nicorandil in addition to continuous intravenous infusion of ATP 150microg/kg/min for 2 minutes
1mg of intracoronary nicorandil in addition to continuous intravenous infusion of ATP 150microg/kg/min for 2 minutes
2mg of intracoronary nicorandil in addition to continuous intravenous infusion of ATP 150microg/kg/min for 2 minutes
20 | years-old | <= |
80 | years-old | > |
Male and Female
Patients who have a 50 to 75% focal stenosis in the coronary artery on diagnostic coronary angiography
younger than 20 years old
older than 80 years old
acute coronary syndrome
heart failure
left main stenosis
post coronary artery bypass graft
220
1st name | Kenichi |
Middle name | |
Last name | Fujii |
Higashi Takarazuka Satoh Hospital
Department of Cardiology
665-0873
2-1 Nagao-cho, Takarazuka-city
0797882200
kfujii350@hotmail.com
1st name | Kenichi |
Middle name | |
Last name | Fujii |
Higashi Takarazuka Satoh Hospital
Department of Cardiology
665-0873
2-1 Nagao-cho, Takarazuka-city
0797882200
kfujii350@hotmail.com
Higashi Takarazuka Satoh Hospital
Higashi Takarazuka Satoh Hospital
Self funding
Higashi Takarazuka Satoh Hospital
2-1 Nagao-cho, Takarazuka-city
0797882200
kfujii350@hotmail.com
NO
2018 | Year | 12 | Month | 01 | Day |
Unpublished
Completed
2017 | Year | 08 | Month | 09 | Day |
2017 | Year | 08 | Month | 30 | Day |
2017 | Year | 10 | Month | 01 | Day |
2018 | Year | 12 | Month | 31 | Day |
2018 | Year | 12 | Month | 01 | Day |
2020 | Year | 06 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000040011
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