Unique ID issued by UMIN | UMIN000035139 |
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Receipt number | R000040053 |
Scientific Title | Analgesic effect evaluation of nerve block during general anesthesia using pupillometry ~ Pilot study ~ |
Date of disclosure of the study information | 2018/12/05 |
Last modified on | 2018/12/05 11:50:16 |
Analgesic effect evaluation of nerve block during general anesthesia using pupillometry ~ Pilot study ~
Analgesic effect evaluation of nerve block during general anesthesia using pupillometry ~ Pilot study ~
Analgesic effect evaluation of nerve block during general anesthesia using pupillometry ~ Pilot study ~
Analgesic effect evaluation of nerve block during general anesthesia using pupillometry ~ Pilot study ~
Japan |
knee osteoarthritis
Anesthesiology |
Others
NO
Pupillometry to detect pain response during general anesthesia for evaluation of analgesic effect of nerve block has been reported.
In this study, we analyze the change in pupil diameter after femoral nerve block, and investigate and analyze useful index for analgesic effect determination.
Efficacy
Exploratory
Pragmatic
time of determination of analgesic effect of nerve block by pupillometry
change in pupil diameter, reaction latency, reaction rate
Observational
20 | years-old | <= |
100 | years-old | >= |
Male and Female
Patients aged 20 years or older who undergo femoral nerve block during general anesthesia
Patients with pupillary dysfunction
Patients with ophthalmic nerve paralysis
Patients using opioids before surgery
Patients using drugs affect pupil diameter change(anticholinergics, dopamine D2 receptor antagonists)
Patients who can not use propofol
10
1st name | |
Middle name | |
Last name | Miho Wakabayashi |
Wakayama medical university
department of anesthesiology
811-1 Kimiidera, Wakayama-city, Wakayama, Japan
073-441-0611
mmasaki@wakayama-med.ac.jp
1st name | |
Middle name | |
Last name | Miho Wakabayashi |
Wakayama medical university
department of anesthesiology
811-1 Kimiidera, Wakayama-city, Wakayama, Japan
073-441-0611
mmasaki@wakayama-med.ac.jp
Wakayama medical university, department of anesthesiology
Wakayama medical university, department of anesthesiology
Other
NO
2018 | Year | 12 | Month | 05 | Day |
Unpublished
Preinitiation
2018 | Year | 12 | Month | 01 | Day |
2018 | Year | 12 | Month | 05 | Day |
2020 | Year | 03 | Month | 31 | Day |
After administration of propofol, ultrasound-guided femoral nerve block is performed and electrical stimulation is performed to an anterior surface of the knee. We measure pupil diameter before and after stimulation, before the administration of the local anesthetic solution, 1 minute, 3 minutes, 5 minutes, 10 minutes, 15 minutes after the administration of the local anesthetic solution.
Also, as a control, electrical stimulation is similarly applied to the anterior surface of the knee on the contralateral side, and pupil diameter are measured.
2018 | Year | 12 | Month | 05 | Day |
2018 | Year | 12 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000040053
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