Unique ID issued by UMIN | UMIN000035303 |
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Receipt number | R000040223 |
Scientific Title | The relationship between methacholine induced cough response, cough receptor sensitivity to capsaicin and a sensation of irritation in the throat |
Date of disclosure of the study information | 2018/12/18 |
Last modified on | 2018/12/18 20:35:31 |
The relationship between methacholine induced cough response, cough receptor sensitivity to capsaicin and a sensation of irritation in the throat
The relationship between methacholine induced cough response, cough receptor sensitivity to capsaicin and a sensation of irritation in the throat
The relationship between methacholine induced cough response, cough receptor sensitivity to capsaicin and a sensation of irritation in the throat
The relationship between methacholine induced cough response, cough receptor sensitivity to capsaicin and a sensation of irritation in the throat
Japan |
healthy adults
Pneumology |
Others
NO
To investigate whether the cough response induced by inhaled methacholine and cough reflex sensitivity to inhaled capsaicin are related to the degree of a sensation of irritation in the throat in healthy adult.
Others
To investigate whether there is a difference in a sensation in the throat caused by inhaled methacholine and capsaicin.
Correlation between the cough response induced by methacholine inhalation and a sensation in the throat.
Correlation between the cough reflex sensitivity to inhaled capsaicin and a sensation in the throat.
Difference in a sensation in the throat caused by inhaled methacholine and capsaicin.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Prevention
Medicine |
visit 1, 3 inhalation of methacholine
visit 2 inhalation of capsaicin
20 | years-old | <= |
Not applicable |
Male and Female
1: subjects with aged 20 years or older
2; subjects without history of respiratory disease and symptoms
3; subjects who can get documentary consent by one's own free will after enough informed consent
4; subjects with NLHQ is less than 17.1.
1; subjects with cardiovascular disease, liver / biliary tree disease, digestive organ disease, immune disease or malignant tumor etc
2; subjects with a low pulmonary function whose 1 second amount is 1 L or less
3; subjects with the risk of pneumothorax and mediastinal emphysema
4: subjects who are allergic to capsaicin
5; pregnant or having a possibility of pregnancy
6; subjects who is lactating
7; Others who judged inappropriate by other research researcher or research sharing doctor
30
1st name | |
Middle name | |
Last name | Kazuo Kasahara |
Kanazawa University Hospital
Respiratory medicine
13-1, Takara-machi, Kanazawa, Ishikawa
076-265-2000
hara0728@staff.kanazawa-u.ac.jp
1st name | |
Middle name | |
Last name | Johsuke Hara |
Kanazawa University Hospital
Respiratory medicine
13-1, Takara-machi, Kanazawa, Ishikawa
076-265-2000
hara0728@staff.kanazawa-u.ac.jp
Kanazawa University Hospital
Kanazawa University Hospital
Other
NO
2018 | Year | 12 | Month | 18 | Day |
Partially published
Open public recruiting
2018 | Year | 11 | Month | 28 | Day |
2018 | Year | 11 | Month | 28 | Day |
2018 | Year | 12 | Month | 18 | Day |
2018 | Year | 12 | Month | 18 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000040223
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