Unique ID issued by UMIN | UMIN000035540 |
---|---|
Receipt number | R000040494 |
Scientific Title | Resveratrol derivative-rich melinjo seed extract in the treatment of chronic periodontitis patients A randomized controlled pilot study |
Date of disclosure of the study information | 2019/01/14 |
Last modified on | 2019/01/14 23:08:54 |
Resveratrol derivative-rich melinjo seed extract in the treatment of chronic periodontitis patients
A randomized controlled pilot study
Resveratrol in the treatment of periodontitis patients
Resveratrol derivative-rich melinjo seed extract in the treatment of chronic periodontitis patients
A randomized controlled pilot study
Resveratrol in the treatment of periodontitis patients
Japan |
Periodontitis
Dental medicine |
Others
NO
The aim of this study was to assess the effect of melinjo seed extract on patients who had been treated previously for periodontitis and were in supportive periodontal therapy.
Efficacy
Confirmatory
The following clinical parameters were recorded at each visit (baseline, week4, week8): (1) pocket depth(PD); (2) clinical attachment level (CAL); (3) bleeding on probing (BOP)
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
NO
NO
Institution is not considered as adjustment factor.
YES
Central registration
2
Treatment
Food |
Patients received 150mg of melinjo seed extract for 8 weeks.
Patients received 150mg of placebo for 8 weeks.
40 | years-old | <= |
Not applicable |
Male and Female
(1) no use of systemic antibiotics or oral anti-microbial agents within the past six months; (2) periodontitis defined as the presence (on fully erupted teeth) of at least one site with a probing depth (PD) 5-7 mm;
(1)severe systemic disease; (2) pregnancy.
18
1st name | |
Middle name | |
Last name | Yuichi Izumi |
Tokyo Medical and Dental University
Department of Periodontology
Yushima 1-5-45 Bunkyo tokyo JAPAN
03-5803-5488
y-izumi.peri@tmd.ac.jp
1st name | |
Middle name | |
Last name | Yuichi Ikeda |
Tokyo Medical and Dental University
Department of Periodontology
Yushima 1-5-45 Bunkyo tokyo JAPAN
03-5803-5488
ikeda.peri@tmd.ac.jp
Tokyo Medical and Dental University
Yamada Bee Company, Inc.
Profit organization
Japan
YES
1286
Tokyo Medical and Dental University Institutional Review Board
Tokyo Medical and Dental University
2019 | Year | 01 | Month | 14 | Day |
Unpublished
Completed
2016 | Year | 03 | Month | 01 | Day |
2016 | Year | 04 | Month | 01 | Day |
2018 | Year | 07 | Month | 31 | Day |
2019 | Year | 01 | Month | 14 | Day |
2019 | Year | 01 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000040494
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |