UMIN-CTR Clinical Trial

Unique ID issued by UMIN UMIN000036089
Receipt number R000041115
Scientific Title Comparison of hemodynamic responses to administration of vasopressin and norepinephrine under general anesthesia: a systematic review and meta-analysis of randomized control trials
Date of disclosure of the study information 2020/01/01
Last modified on 2020/10/27 09:51:32

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Basic information

Public title

Comparison of hemodynamic responses to administration of vasopressin and norepinephrine under general anesthesia: a systematic review and meta-analysis of randomized control trials

Acronym

Comparison of hemodynamic responses to administration of vasopressin and norepinephrine under general anesthesia

Scientific Title

Comparison of hemodynamic responses to administration of vasopressin and norepinephrine under general anesthesia: a systematic review and meta-analysis of randomized control trials

Scientific Title:Acronym

Comparison of hemodynamic responses to administration of vasopressin and norepinephrine under general anesthesia

Region

Japan


Condition

Condition

Surgical patients with tracheal intubation

Classification by specialty

Anesthesiology

Classification by malignancy

Others

Genomic information

NO


Objectives

Narrative objectives1

to examine heart rate (HR), mean blood pressure (MBP), and central venous pressure (CVP) to determine whether vasopressin superior to norepinephrine for the hemodynamic responses.

Basic objectives2

Efficacy

Basic objectives -Others


Trial characteristics_1


Trial characteristics_2


Developmental phase



Assessment

Primary outcomes

heart rate (HR), mean blood pressure (MBP), and central venous pressure (CVP)

Key secondary outcomes



Base

Study type

Others,meta-analysis etc


Study design

Basic design


Randomization


Randomization unit


Blinding


Control


Stratification


Dynamic allocation


Institution consideration


Blocking


Concealment



Intervention

No. of arms


Purpose of intervention


Type of intervention


Interventions/Control_1


Interventions/Control_2


Interventions/Control_3


Interventions/Control_4


Interventions/Control_5


Interventions/Control_6


Interventions/Control_7


Interventions/Control_8


Interventions/Control_9


Interventions/Control_10



Eligibility

Age-lower limit

18 years-old <=

Age-upper limit

100 years-old >

Gender

Male and Female

Key inclusion criteria

Our search encompassed all trials that compared the measures associated with hemodynamic changes of heart rate (HR), mean blood pressure (MBP), and central venous pressure (CVP) between vasopressin and norepinephrine during general anesthesia.

Key exclusion criteria

pediatrics, ICU patients

Target sample size

150


Research contact person

Name of lead principal investigator

1st name Hiroshi
Middle name
Last name Hiroshi Hoshijima

Organization

Saitama Medical University Hospital

Division name

Anesthesiology

Zip code

350-0495

Address

38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan

TEL

0492761271

Email

hhoshi6@gmail.com


Public contact

Name of contact person

1st name Hiroshi
Middle name
Last name Hoshijima

Organization

Saitama Medical University Hospital

Division name

Anesthesiology

Zip code

350-0495

Address

38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan

TEL

0492761271

Homepage URL


Email

hhoshi6@gmail.com


Sponsor or person

Institute

Saitama Medical University Hospital

Institute

Department

Personal name



Funding Source

Organization

Saitama Medical University Hospital

Organization

Division

Category of Funding Organization

Other

Nationality of Funding Organization



Other related organizations

Co-sponsor


Name of secondary funder(s)



IRB Contact (For public release)

Organization

Saitama Medical University Hospital

Address

38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan

Tel

0492761271

Email

hhoshi6@gmail.com


Secondary IDs

Secondary IDs

NO

Study ID_1


Org. issuing International ID_1


Study ID_2


Org. issuing International ID_2


IND to MHLW



Institutions

Institutions



Other administrative information

Date of disclosure of the study information

2020 Year 01 Month 01 Day


Related information

URL releasing protocol


Publication of results

Unpublished


Result

URL related to results and publications


Number of participants that the trial has enrolled


Results


Results date posted


Results Delayed


Results Delay Reason


Date of the first journal publication of results


Baseline Characteristics


Participant flow


Adverse events


Outcome measures


Plan to share IPD


IPD sharing Plan description



Progress

Recruitment status

Main results already published

Date of protocol fixation

2019 Year 03 Month 04 Day

Date of IRB

2018 Year 04 Month 07 Day

Anticipated trial start date

2019 Year 03 Month 04 Day

Last follow-up date

2020 Year 01 Month 01 Day

Date of closure to data entry


Date trial data considered complete


Date analysis concluded



Other

Other related information

We conducted a comprehensive search of the literature using PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, and Scopus.


Management information

Registered date

2019 Year 03 Month 05 Day

Last modified on

2020 Year 10 Month 27 Day



Link to view the page

Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000041115


Research Plan
Registered date File name

Research case data specifications
Registered date File name

Research case data
Registered date File name