Unique ID issued by UMIN | UMIN000036252 |
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Receipt number | R000041292 |
Scientific Title | Study on the pathophysiology of neuro-psychiatric disorders using a PET tracer ([18F]BCPP-EF) |
Date of disclosure of the study information | 2019/04/01 |
Last modified on | 2022/03/22 10:25:50 |
Study on the pathophysiology of neuro-psychiatric disorders using a PET tracer ([18F]BCPP-EF)
Mitochondria and microglia PET
Study on the pathophysiology of neuro-psychiatric disorders using a PET tracer ([18F]BCPP-EF)
Mitochondria and microglia Brain-PET
Japan |
Dementia, Mild cognitive impairment, psychiatric disorders
Neurology | Psychiatry | Adult |
Others
NO
The aim of this study is to examine the pathophysiology of dementia, using PET tracers for mitochondria and neuroinflammation.
Bio-availability
Exploratory
Explanatory
Not applicable
Elucidation of pathophysiology of the diseases by examining the binding of PET tracers.
Correlation of the tracer binding with psychological and MRI data
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Diagnosis
Other |
PET measurement after intravenous tracer injection
20 | years-old | <= |
85 | years-old | > |
Male and Female
1.Healthy participants aged 20 to 84 years
2.Individuals who have no history of psychiatric disease
3.Individuals who are right-handed
4.Individuals who are consent to participate in this study
5.Critetria for elderly subject: 1) Individuals with Mini-mental state examination scores over 26 at screening, 2) Individuals with Clinical dementia rating scale score 0, 3)Individuals whose ADL is normal without any memory problems
6. Patients with dementia, psychiatric disorders (aged 20 to 84 years)
1.Individuals who have a history of traumatic brain injury with an unconsciousness lasting more than 5 minutes
2.Individuals who have a history of organic brain disease
3.Individuals who have a history of substance dependence
4.Individuals who are taking central nervous system stimulants
5.Individuals who have a history of disorders of consciousness and/or seizure
6.Individuals who have a chronic headache
7.Individuals who have a risk for MRI scan
8. Individuals who are considered unsuitable by doctors in charge
60
1st name | Yasuomi |
Middle name | |
Last name | Ouchi |
Hamamatsu University School of Medicine
Department of Biofunctional Imaging
431-3192
1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka, Japan
053-435-2466
ouchi@hama-med.ac.jp
1st name | Yasuomi |
Middle name | |
Last name | Ouchi |
Hamamatsu University School of Medicine
Department of Biofunctional Imaging
431-3192
1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka, Japan
053-435-2466
ouchi@hama-med.ac.jp
Department of Biofunctional Imaging,
Hamamatsu University School of Medicine
Ministry of Education, Culture, Sports, Science and Technology
Japanese Governmental office
Japan
Hamamatsu Medical Photonics Foundation
Hamamatsu Photonics KK
Hamamatsu University School of Medicine
1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka, Japan
053-435-2680
rinri@hama-med.ac.jp
NO
2019 | Year | 04 | Month | 01 | Day |
Unpublished
Open public recruiting
2019 | Year | 03 | Month | 08 | Day |
2018 | Year | 10 | Month | 05 | Day |
2019 | Year | 04 | Month | 08 | Day |
2023 | Year | 03 | Month | 15 | Day |
2023 | Year | 03 | Month | 15 | Day |
2023 | Year | 03 | Month | 15 | Day |
2023 | Year | 03 | Month | 31 | Day |
2019 | Year | 03 | Month | 19 | Day |
2022 | Year | 03 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000041292
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