Unique ID issued by UMIN | UMIN000036598 |
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Receipt number | R000041661 |
Scientific Title | Evaluations of pathogenesis of cardiovascular disease and cardiovascular event risk in patients undergoing hemodialysis by biomarkers for cardiovascular disease |
Date of disclosure of the study information | 2019/05/01 |
Last modified on | 2022/10/27 11:14:48 |
Evaluations of pathogenesis of cardiovascular disease and cardiovascular event risk in patients undergoing hemodialysis by biomarkers for cardiovascular disease
Biomarkers for cardiovascular disease in hemodialysis patients
Evaluations of pathogenesis of cardiovascular disease and cardiovascular event risk in patients undergoing hemodialysis by biomarkers for cardiovascular disease
Biomarkers for cardiovascular disease in hemodialysis patients
Japan |
End-stage renal disease
Cardiology | Nephrology |
Others
NO
To clarify the significance of biomarkers for cardiovascular disease in patients undergoing hemodialysis
Others
Associations of biomarkers for cardiovascular disease with cardiovascular events and vascular calcification
Exploratory
Others
Not applicable
Association of biomarkers for cardiovascular disease such as Pentraxin 3 and soluble lectin-like oxidized LDL receptor-1 with cardiovascular events in hemodialysis patients for 2 years follow-up period
Clinical and laboratory factors associated with Pentraxin 3 and soluble lectin-like oxidized LDL receptor-1 levels in hemodialysis patients including all cause mortality
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1. Patients undergoing hemodialysis at Oyokyo Kidney Research Institute Hirosaki Hospital
2. Minimal dialysis vintage 3 month
3. Age more than 20 years old and older
4. Patients who can understand the purpose and content of this study and give written informed consent
1.Patients with active infectious disease
2.History of autoimmune disease
3.History of malignancy
4.Kidney transplantation planned
250
1st name | Hiroshi |
Middle name | |
Last name | Osawa |
Hirosaki University Hospital
Department of General Medicine
0368563
53 Hon-cho, Hirosaki, Aomori, Japan
0172395177
osawa@hirosaki-u.ac.jp
1st name | Hiroshi |
Middle name | |
Last name | Osawa |
Hirosaki University Hospital
Department of General Medicie
0368563
53 Hon-cho, Hirosaki, Aomori, Japan
0172395177
osawa@hirosaki-u.ac.jp
Department of General Medicine, Hirosaki University Hospital
Oyokyo Kidney Research Institute
Other
Oyokyo Kidney Research Institute Hirosaki Hospital
The Comitee of Medical Ethics of Hirosaki University Graduate School of Medicine
5 Zaifu-cho, Hirosaki, Aomori, Japan
0172395194
jm5194@hirosaki-u.ac.jp
NO
2019 | Year | 05 | Month | 01 | Day |
Unpublished
256
A total of 256 participants were finally enrolled on May 20, 2020 through the screening for eligibility since May 2019.
One patient was found to have recent history of operation for renal cell carcinoma and was excluded from analysis.
2020 | Year | 05 | Month | 21 | Day |
Completed
2019 | Year | 03 | Month | 13 | Day |
2019 | Year | 04 | Month | 16 | Day |
2019 | Year | 05 | Month | 07 | Day |
2022 | Year | 05 | Month | 31 | Day |
2022 | Year | 06 | Month | 30 | Day |
2022 | Year | 07 | Month | 20 | Day |
2022 | Year | 08 | Month | 31 | Day |
1.Prospective observational study
2.Patients are enrolled from May 7,2019 to April 30, 2019 according to the inclusion criteria.
3.Participants are prospectively followed for 2 years to investigate associations of biomarkers at baseline with cardiovascular evens.
2019 | Year | 04 | Month | 25 | Day |
2022 | Year | 10 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000041661
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