Unique ID issued by UMIN | UMIN000036566 |
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Receipt number | R000041662 |
Scientific Title | Pharmacokinetic study of continuous-infusional 5-FU for esophageal carcinoma |
Date of disclosure of the study information | 2019/04/21 |
Last modified on | 2021/08/12 17:18:50 |
Pharmacokinetic study of continuous-infusional 5-FU for esophageal carcinoma
Pharmacokinetic study of 5-FU for esophageal carcinoma
Pharmacokinetic study of continuous-infusional 5-FU for esophageal carcinoma
Pharmacokinetic study of 5-FU for esophageal carcinoma
Japan |
Esophageal carcinoma
Gastrointestinal surgery |
Malignancy
NO
To determine inter-individual variability in pharmacokinetics of BSA based 5-FU continuous intravenous infusion for esophageal carcinoma.
Pharmacokinetics
Distribution of area under the time-concentration couve (AUC) of 5-FU
Correlation of AUC and 5-FU related efficacy and adverse events
Gender difference on AUC
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients who are planned for treatment with neoadjuvant FP therapy (CDDP 80mg/m2 + 5-FU 800mg/m2)
Presence of pleural effusion or ascites at registration
50
1st name | Hirofumi |
Middle name | |
Last name | Kawakubo |
Keio University, School of Medicine
Department of Surgery
1608582
35 Shinanomachi, Shinjuku-ku, Tokyo, Japan
0353633802
hkawakubo@z3.keio.jp
1st name | Kazuaki |
Middle name | |
Last name | Matsui |
Keio University, School of Medicine
Department of Surgery
1608582
35 Shinanomachi, Shinjuku-ku, Tokyo, Japan
0353633802
k.matsui@keio.jp
Keio University, School of Medicine
Keio University, School of Medicine
Other
Keio University, School of Medicine
35 Shinanomachi, Shinjuku-ku, Tokyo, Japan
0333531211
med-rinri-jimu@adst.keio.ac.jp
NO
2019 | Year | 04 | Month | 21 | Day |
Unpublished
Completed
2019 | Year | 02 | Month | 26 | Day |
2019 | Year | 02 | Month | 26 | Day |
2019 | Year | 04 | Month | 01 | Day |
2021 | Year | 03 | Month | 31 | Day |
Observational study
2019 | Year | 04 | Month | 21 | Day |
2021 | Year | 08 | Month | 12 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000041662
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