Unique ID issued by UMIN | UMIN000036987 |
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Receipt number | R000042137 |
Scientific Title | Dose-response relationship of polysuilfides enriched garlic intake on fractional exhaled hydrogen sulfide and the physiological responses to high-intensity continous exercise |
Date of disclosure of the study information | 2019/06/06 |
Last modified on | 2019/06/06 19:32:08 |
Dose-response relationship of polysuilfides enriched garlic intake on fractional exhaled hydrogen sulfide and the physiological responses to high-intensity continous exercise
Dose-response relationship of polysuilfides enriched garlic intake on fractional exhaled hydrogen sulfide and the physiological responses to high-intensity continous exercise
Dose-response relationship of polysuilfides enriched garlic intake on fractional exhaled hydrogen sulfide and the physiological responses to high-intensity continous exercise
Dose-response relationship of polysuilfides enriched garlic intake on fractional exhaled hydrogen sulfide and the physiological responses to high-intensity continous exercise
Asia(except Japan) |
Recreationally Active
Adult |
Others
NO
To characterize pharmacokinetic responses of plasma hydrogen sulfides and blood pressure responses following different doses of polysulfide enriched garlic over a 24-hour period
Others
To asses the influence of polysulfide enriched garlic on physiological responses to high-intensity continous exercise tolerance, cognitive function and high-intensity intermittent exercise
Confirmatory
Not applicable
Pharmacokinetic dose-reponses (plasma hydrogen sulfide)
Resting blood pressure (systolic blood pressure, diastolic blood pressure and mean arterial pressure)
Fractional exhaled hydrogen sulfide
Niric oxide level
Renal function (Urea, Nitrogen, Creatine)
Blood glucose and blood lactate
Plasma sodium and potassium
Oxygen cost of exercise
Oxidant and antioxidant markers
Cognitive function
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Placebo
2
Treatment
Food |
Sandwich containing polysulfide enriched garlic 2g/4g/6g
Placebo sandwich not containing polysulfide enriched garlic
18 | years-old | <= |
60 | years-old | > |
Male and Female
(1) Healthy adults
(2) free from injury
(3) Do not have any current or history of cardiovascular, metabolic or pulmonary disease
(4) No contraindication for blood sampling procedure
(5) Pass The Physical Activity Readiness Questionnaire (PAR-Q)
(1) Smoker
(2) Individual who consume any dietary supplements, quasi drugs or medicines within past 4 weeks
(3) On medication
(4) Receiver of blood transfusion within 1 month prior to screening
(5) Receiver of any investigational research agent prior to 30 days of experimental trial and individual who have a history of or current clinically significant disease
(6) Clinical population or an individual with heart/vascular related problem
(7) Individual with the medical histories of alcoholism or drug dependence
(8) Individual who have contraindication with high intensity exercise
8
1st name | Adam |
Middle name | |
Last name | Linoby |
Universiti Teknologi MARA
Faculty of Sports Science and Recreation
70300
UiTM Cawangan Negeri Sembilan, Kampus Seremban, Jalan Seremban Tiga/1, Seremban 3, Seremban, Negeri Sembilan, Malaysia
+60133632005
linoby@uitm.edu.my
1st name | Adam |
Middle name | |
Last name | Linoby |
Universiti Teknologi MARA
Faculty of Sports Science and Recreation
70300
UiTM Cawangan Negeri Sembilan, Kampus Seremban, Jalan Seremban Tig
+60133632005
https://seremban.uitm.edu.my/
linoby@uitm.edu.my
Faculty of Sports Science and Recreation, Universiti Teknologi MARA
Fundamental Research Grant Scheme, Ministry of Higher Education (Malaysia)
Outside Japan
Malaysia
Faculty of Sports Science and Recreation, Universiti Teknologi MARA
UiTM Cawangan Negeri Sembilan, Kampus Seremban, Jalan Seremban Tiga/1, Seremban 3, Seremban, Negeri Sembilan, Malaysia
+606-6342409
shari0971@uitm.edu.my
NO
2019 | Year | 06 | Month | 06 | Day |
Unpublished
8
Completed
2017 | Year | 12 | Month | 01 | Day |
2019 | Year | 04 | Month | 30 | Day |
2019 | Year | 06 | Month | 06 | Day |
2020 | Year | 12 | Month | 01 | Day |
2019 | Year | 06 | Month | 06 | Day |
2019 | Year | 06 | Month | 06 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000042137
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