Unique ID issued by UMIN | UMIN000037033 |
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Receipt number | R000042191 |
Scientific Title | The feasibility study for screening of early stage of lung cancer by novel urinary biomarker using protein fragments: a prospective study |
Date of disclosure of the study information | 2019/06/12 |
Last modified on | 2021/04/01 17:45:04 |
The feasibility study for screening of early stage of lung cancer by novel urinary biomarker using protein fragments: a prospective study
The feasibility study for screening of early stage of lung cancer by novel urinary biomarker using protein fragments: a prospective study
The feasibility study for screening of early stage of lung cancer by novel urinary biomarker using protein fragments: a prospective study
The feasibility study for screening of early stage of lung cancer by novel urinary biomarker using protein fragments: a prospective study
Japan |
Idiopathic pulmonary fibrosis (IPF)
Pneumology |
Malignancy
NO
The aim of this study is to investigate the detectability of lung cancer of urinary protein fragment and compare the detectability of the fragment with established blood tumour markers.
Efficacy
Comparison of detectability of lung cancer of urinary protein fragment and established blood tumour markers at the time of lung cancer diagnosis in patients with IPF
1)Comparison of detectability of lung adenocarcinoma of urinary protein fragment and CEA at the time of diagnosis of lung adenocarcinoma in patients with IPF
2) Comparison of detectability of lung squamous cell carcinoma of urinary protein fragment and established blood tumour markers (SCC, CYFRA) at the time of diagnosis of lung squamous cell carcinoma in patients with IPF
3)Comparison of the value of urinary protein fragments before and after diagnosis of lung cancer
4)Comparison of the value of urinary protein fragments in IPF patients with lung cancer and without lung cancer.
5)Comparison of the value of urinary protein fragments in IPF patients who experienced acute exacerbation and IPF patients without exacerbation
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1)Patients aged equal to or greater than 20 years-old.
2)Patients diagnosed as IPF based of an Official ATS/ERS/JRS/ALAT Clinical Practice Guideline.
3)Patients who had a detailed briefing of the trial prior to the enrollment and voluntarily signed a consent form
1)Patients who have abnormal shadow (more than or equal to 1.0 cm) clinicaly suspected lung cancer by high resolution CT.
2)Patients who have proteinuria, positive urine sugar or urine occult blood in urinalysis (more than or equal to 2+).
3)Patients who have renal dysfunction (Serum levels of creatinine > 2.0 mg/dl).
4)Patients who have alcohol or drug dependence or who are suspected to have alcohol or drug dependence.
5)Patients who is pregnant or who is suspected to be pregnant.
6)Patients who was enrolled another clinical trial and was prescribed a study drug within one month.
7)Patients whose attending physicians consider to be inappropriate for this study.
120
1st name | Masamitsu |
Middle name | |
Last name | Nakazato |
University of Miyazaki
Neurology, Respirology, Endocrinology and Metabolism, Internal Medicine, Faculty of Medicine
889-1692
5200 Kihara, Kiyotake, Miyazaki, Japan
0985-85-2965
nakazato@med.miyazaki-u.ac.jp
1st name | Hironobu |
Middle name | |
Last name | Tsubouchi |
University of Miyazaki
Neurology, Respirology, Endocrinology and Metabolism, Internal Medicine, Faculty of Medicine
889-1692
5200 Kihara, Kiyotake, Miyazaki, Japan
0985-85-2965
hironobu_tsubouchi@med.miyazaki-u.ac.jp
University of Miyazaki
Japan Agency for Medical Research and Development
Japanese Governmental office
University of Miyazaki
5200 Kihara, Kiyotake, Miyazaki, Japan
0985-85-9010
igakubu_kenkyu@med.miyazaki-u.ac.jp
NO
宮崎大学医学部附属病院
長崎大学病院
産業医科大学病院
鳥取大学医学部附属病院
2019 | Year | 06 | Month | 12 | Day |
Unpublished
No longer recruiting
2019 | Year | 03 | Month | 25 | Day |
2019 | Year | 06 | Month | 06 | Day |
2019 | Year | 06 | Month | 17 | Day |
2023 | Year | 03 | Month | 31 | Day |
2024 | Year | 03 | Month | 31 | Day |
No other related information
2019 | Year | 06 | Month | 12 | Day |
2021 | Year | 04 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000042191
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