Unique ID issued by UMIN | UMIN000043925 |
---|---|
Receipt number | R000042200 |
Scientific Title | Safety Assessment of Ultra-low-flow and Low-flow Sevoflurane Anesthesia Using Carbon Dioxide Absorbent YABASHI LIME-f |
Date of disclosure of the study information | 2021/04/14 |
Last modified on | 2021/10/14 10:42:06 |
Safety Assessment of Ultra-low-flow and Low-flow Sevoflurane Anesthesia Using Carbon Dioxide Absorbent YABASHI LIME-f
SAULSAY
Safety Assessment of Ultra-low-flow and Low-flow Sevoflurane Anesthesia Using Carbon Dioxide Absorbent YABASHI LIME-f
SAULSAY
Japan |
Colon cancer, Benign colorectal disease
Surgery in general | Gastrointestinal surgery |
Malignancy
NO
In this study, we use Yabashilime-f and perform respiratory control under sevoflurane anesthesia with a fresh gas flow rate of 0.5 L / min (very low flow rate), 1 L / min (low flow rate), or 2 L / min of normal flow rate. In colorectal disease surgery, we will evaluate the concentration of Compound A in the anesthesia circuit over time and the presence or absence of postoperative acute kidney injury onset in patients. This will examine whether sevoflurane very low flow anesthesia and low flow anesthesia surgery can be performed without causing renal dysfunction.
Safety
Measurement of Compound A concentration in anesthesia circuit over time
Whether the patient has postoperative acute kidney disease
Interventional
Parallel
Randomized
Individual
Single blind -participants are blinded
Dose comparison
NO
YES
Institution is not considered as adjustment factor.
NO
No need to know
3
Treatment
Device,equipment |
fresh gas frow rate 0.5 L/h
fresh gas frow rate 1 L/h
fresh gas frow rate 2 L/h
20 | years-old | <= |
Not applicable |
Male and Female
Scheduled colon cancer resection ( over 6 hours anesthesia )
Renal function is normal (eGFR 90 or more) and liver function is normal (total bilirubin is 1.5 times or less of the upper limit of the medical institution's standard value and AST and ALT are 2.5 times or less of the upper limit of the medical institution's standard value)
18
1st name | Kimitoshi |
Middle name | |
Last name | Nishiwaki |
Nagoya university graduate school of medicine
Department of anesthesiology
466-8550
65 tsurumai showa nagoya
052-744-2340
nishi@med.nagoya-u.ac.jp
1st name | Takahiro |
Middle name | |
Last name | Ando |
Nagoya university hospital
Department of surgery section
466-8550
65 tsurumai showa nagoya
052-744-2340
bakagarasu7@gmail.com
Nagoya university graduate school of medicine
Nagoya university graduate school of medicine
Other
Nagoya university graduate school of medicine
65 tsurumai showa nagoya
052-744-2973
ethics@med.nagoya-u.ac.jp
NO
2021 | Year | 04 | Month | 14 | Day |
Unpublished
Open public recruiting
2019 | Year | 08 | Month | 15 | Day |
2019 | Year | 08 | Month | 15 | Day |
2019 | Year | 08 | Month | 15 | Day |
2023 | Year | 03 | Month | 31 | Day |
2021 | Year | 04 | Month | 14 | Day |
2021 | Year | 10 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000042200
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |