Unique ID issued by UMIN | UMIN000037326 |
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Receipt number | R000042545 |
Scientific Title | Biomarker study of a multicentre, open-label, randomized Phase III Study of Atezolizumab with Platinum-Pemetrexed with or without Bevacizumab for Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer WJOG11218L/APPLE (APPLE Biomarker study) (WJOG11218LTR) |
Date of disclosure of the study information | 2019/07/10 |
Last modified on | 2021/01/11 08:52:47 |
Biomarker study of a multicentre, open-label, randomized Phase III Study of Atezolizumab with Platinum-Pemetrexed with or without Bevacizumab for Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer WJOG11218L/APPLE (APPLE Biomarker study) (WJOG11218LTR)
Apple biomarker study
Biomarker study of a multicentre, open-label, randomized Phase III Study of Atezolizumab with Platinum-Pemetrexed with or without Bevacizumab for Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer WJOG11218L/APPLE (APPLE Biomarker study) (WJOG11218LTR)
Apple biomarker study
Japan |
advanced non-squamous non-small cell lung cancer
Pneumology | Hematology and clinical oncology |
Malignancy
NO
To elucidate patients whose value of VEGF-A and soluble PD-L1 in serum before treatment can be predictive of response to immunotherapies combined with an anti-antiogenesis antibody, Bevacizumab in a multicentre, open-label, randomized Phase III Study of Atezolizumab with Platinum-Pemetrexed with or without Bevacizumab for Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer
Others
Exploration of biomarkers to predict response to platinum-combined immunotherapies
Exploratory
Others
Not applicable
Exploration of biomarkers to predict response to platinum-combined immunotherapies
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Subjects who agreed by consent forms to attend this study among those who attended WJOG 11218L.
Subjects who do not agree by consent forms to attend this study.
200
1st name | Isamu |
Middle name | |
Last name | Okamoto |
Kyushu University Hospital
Department of Respiratory Medicine
812-8582
Maidashi 3-1-1, Higashi-ku, Fukuoka
092-642-5378
iokamoto@kokyu.med.kyushu-u.ac.jp
1st name | Shinichiro |
Middle name | |
Last name | Nakamura |
West Japan Oncology Group
WJOG datacenter
556-0016
Namba Plaza Bldg. 304-1-5-7, Motomachi Naniwa-ku, Osaka, JAPAN
06-6633-7400
datacenter@wjog.jp
West Japan Oncology Group
none
Self funding
Kyushu University Institutional Review Board for Clinical Research
Maidashi 3-1-1, Higashi-ku, Fukuoka
092-642-5774
bynintei@jimu.kyushu-u.ac.jp
NO
2019 | Year | 07 | Month | 10 | Day |
Unpublished
No longer recruiting
2019 | Year | 06 | Month | 28 | Day |
2019 | Year | 09 | Month | 11 | Day |
2019 | Year | 08 | Month | 01 | Day |
2025 | Year | 01 | Month | 19 | Day |
This is the observational study to collect blood once before treatment.
After August 2019, all patients are eligible who consented to attend this study by the document form among those who attended the WJOG11218L.
2019 | Year | 07 | Month | 10 | Day |
2021 | Year | 01 | Month | 11 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000042545
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