Unique ID issued by UMIN | UMIN000037422 |
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Receipt number | R000042659 |
Scientific Title | An open-labeled single arm study on improvement of cognitive function by istradefylline for parkinson disease |
Date of disclosure of the study information | 2019/08/01 |
Last modified on | 2023/07/23 11:26:07 |
An open-labeled single arm study on improvement of cognitive function by istradefylline for parkinson disease
A study on improvement of cognitive function by istradefylline for parkinson disease
An open-labeled single arm study on improvement of cognitive function by istradefylline for parkinson disease
An open-labeled single arm study on improvement of cognitive function by istradefylline for parkinson disease
Japan |
Parkinson disease
Neurology |
Others
NO
To validate whether istradefylline improves camptocormia of Parkinson disease.
Efficacy
Primary outcome is the angle of camptocormia
Secondary outcomes are Movement Disorder Society-Unified Parkinson Disease Rating Scale(MDS-UPDRS), Non-motor symptoms scales.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Prescription istradefylline 20 mg for 1 month, and if there are no side effects, increase to 40 mg and prescribe for 2 months.
40 | years-old | <= |
85 | years-old | > |
Male and Female
1. The patients meet clinically established or clinically probable cases of clinical diagnostic criteria of Parkinson disease by Movement Disorder Society
2. The item of Attention/memory in NMSS is 1 or more.
3. The patient is treated with drugs that include L-dopa
4. The age of patients is 40 to 85years old.
5. Written consent has been obtained
1. Istradefylline has been prescribed.
2. The patient can not stand.
3. The angle of camptocormia is less than 10 degrees.
25
1st name | Masahiro |
Middle name | |
Last name | Kanai |
Ichinomiya Nishi Hospital
Neurology
494-0001
1, Kaimei-hira, Ichinomiya-city, Aichi, 494-0001, Japan
0586480077
masabilliard35@yahoo.co.jp
1st name | Masahiro |
Middle name | |
Last name | Kanai |
Ichinomiya Nishi Hospital
Neurology
494-0001
1, Kaimei-hira, Ichinomiya-city, Aichi, 494-0001, Japan
0586480077
masabilliard35@yahoo.co.jp
Ichinomiya Nishi Hospital
none
Self funding
Ichinomiya Nishi Hospital
1, Kaimei-hira, Ichinomiya-city, Aichi,
0586480077
matsubara@anzu.or.jp
NO
2019 | Year | 08 | Month | 01 | Day |
Unpublished
14
Completed
2019 | Year | 02 | Month | 01 | Day |
2019 | Year | 02 | Month | 15 | Day |
2019 | Year | 08 | Month | 01 | Day |
2021 | Year | 08 | Month | 01 | Day |
2019 | Year | 07 | Month | 18 | Day |
2023 | Year | 07 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000042659
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