Unique ID issued by UMIN | UMIN000037461 |
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Receipt number | R000042685 |
Scientific Title | Mechanism of carcinogenesis of thyroid cancer in young age |
Date of disclosure of the study information | 2019/07/24 |
Last modified on | 2019/07/23 22:48:49 |
Mechanism of carcinogenesis of thyroid cancer in young age
Mechanism of carcinogenesis of thyroid cancer in young age
Mechanism of carcinogenesis of thyroid cancer in young age
Mechanism of carcinogenesis of thyroid cancer in young age
Japan |
Papillary thyroid carcinoma
Endocrine surgery |
Malignancy
YES
The aim of this study is to elucidate the mechanism of carcinogenesis of thyroid cancer in young age.
Others
The aim of this study was to investigate the frequency of BRAF mutation in both adult and pediatric patients, as well as the relationship between mutation rate and clinicopathological features of PTCs in our institution.
The mutation of BRAF, rearrangements of RET/PTC1, RET/PTC3, ETV6/NTRK3, ETV6NTRK in papillary thyroid carcinomas are analyzed.
Association between mutation/rearrangements and clinicopathologicalfeatures are assessed.
Observational
13 | years-old | <= |
80 | years-old | >= |
Male and Female
The studied cases were selected from patients who underwent thyroid resection and were pathologically diagnosed with PTC.
Tumors with
1. extensive fibrosis
2. calcification
3. hematoma
4. cystic lesions
are excluded from the study.
50
1st name | Shoko |
Middle name | |
Last name | Kure |
Nippon Medical School
Department of Integrated Diagnostic Pathology
113-8602
1-1-5, Sendagi Bunkyoku, Tokyo
03-3822-2131
skure@nms.ac.jp
1st name | Shoko |
Middle name | |
Last name | Kure |
Nippon Medical School
Department of Integrated Diagnostic Pathology
113-8602
1-1-5, Sendagi Bunkyoku, Tokyo
03-3822-2131
skure@nms.ac.jp
Nippon Medical School
The Children's Cancer Association of Japan
Non profit foundation
Center for Clinical Research
1-1-5, Sendagi Bunkyoku, Tokyo
03-3822-2131
officetokutei@nms.ac.jp
NO
2019 | Year | 07 | Month | 24 | Day |
Unpublished
40
No longer recruiting
2017 | Year | 11 | Month | 01 | Day |
2018 | Year | 01 | Month | 26 | Day |
2018 | Year | 01 | Month | 26 | Day |
2018 | Year | 09 | Month | 30 | Day |
On going
2019 | Year | 07 | Month | 23 | Day |
2019 | Year | 07 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000042685
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