Unique ID issued by UMIN | UMIN000037903 |
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Receipt number | R000043195 |
Scientific Title | Effects and feasibility of branched chain amino acid combined with exercise in convalescent patients: A crossover trial |
Date of disclosure of the study information | 2019/09/03 |
Last modified on | 2021/09/02 17:48:23 |
Effects and feasibility of branched chain amino acid combined with exercise in convalescent patients: A crossover trial
Effects and feasibility of branched chain amino acid combined with exercise in convalescent patients
Effects and feasibility of branched chain amino acid combined with exercise in convalescent patients: A crossover trial
Effects and feasibility of branched chain amino acid combined with exercise in convalescent patients
Japan |
Convalescent patients after orthopadic surgery, stroke and lower limb amputee
Neurology | Orthopedics | Neurosurgery |
Plastic surgery | Rehabilitation medicine |
Others
NO
Using randomized, crossover trial, This study examined the feasibility of exercise combined with branched chain amino acid supplementation to physical function.
Efficacy
Confirmatory
Pragmatic
Phase II
Quadriceps muscle thickness, cross-sectional aera of the brachium:
Evaluations were conducted before starting the intervention, after each 1-month supplementation period, and after the washout period.
Knee extensor strength
Grip strength
Timed Up and Go test
Functional Indepndence Measure
Energy consumption
Energy intake
Interventional
Cross-over
Randomized
Individual
Single blind -participants are blinded
Placebo
YES
NO
Institution is not considered as adjustment factor.
YES
Numbered container method
2
Treatment
Food |
Branched amino acid supplement
3.4g(6.8g)/ 1 month
starch 1.2g/ 1 month
20 | years-old | <= |
Not applicable |
Male and Female
Convalescent patients after orthopedic surgery, stroke and lower limb amuptee.
Patients with no deglutition disorder.
1) Persons with renal disorder who need to
protein restriction (eGFR <60)
2) Patients using BCAA formulation for
metabolic liver dysfunction and cirrhosis
3) Patients with dementia
4) Patients with the depression or
schizophrenic disorder
5) Patients with untreated cardio-vascular
disorder
56
1st name | Takashi |
Middle name | |
Last name | Ikeda |
Showa University
School of Nursing and Rehabilitation sciences
227-8518
2-1-1, Fujigaoka Aoba YOKOHAMA, KANAGAWA
+810459742221
tk.ikeda@nr.showa-u.ac.jp
1st name | Takashi |
Middle name | |
Last name | Ikeda |
Showa University
School of Nursing and Rehabilitation sciences
227-8518
2-1-1, Fujigaoka Aoba YOKOHAMA, KANAGAWA
+810459742221
tk.ikeda@nr.showa-u.ac.jp
Showa University Fujigaoka Hospital
Grant-in-Aid for Scientific Research
Japanese Governmental office
Japan
Showa University Fujigaoka Hospital Ethics Committee
1-1-1, Fujigaoka Aoba YOKOHAMA, KANAGAWA
+81 045-974-2221
f-irb@cmed.showa-u.ac.jp
NO
F2019C09
昭和大学藤が丘リハビリテーション病院: Showa University Fujigaoka Rehabilitation Hospital
2019 | Year | 09 | Month | 03 | Day |
Unpublished
Completed
2019 | Year | 07 | Month | 21 | Day |
2019 | Year | 07 | Month | 21 | Day |
2019 | Year | 09 | Month | 15 | Day |
2021 | Year | 03 | Month | 31 | Day |
2021 | Year | 05 | Month | 31 | Day |
2021 | Year | 05 | Month | 31 | Day |
2021 | Year | 08 | Month | 31 | Day |
2019 | Year | 09 | Month | 02 | Day |
2021 | Year | 09 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000043195
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