Unique ID issued by UMIN | UMIN000038072 |
---|---|
Receipt number | R000043331 |
Scientific Title | Randomized clinical trial of CAREDYNE SHIELD for dentin hypersensitivity |
Date of disclosure of the study information | 2019/09/22 |
Last modified on | 2022/08/20 07:25:59 |
Randomized clinical trial of CAREDYNE SHIELD for dentin hypersensitivity
Randomized clinical trial of CAREDYNE SHIELD for dentin hypersensitivity
Randomized clinical trial of CAREDYNE SHIELD for dentin hypersensitivity
Randomized clinical trial of CAREDYNE SHIELD for dentin hypersensitivity
Japan |
Dentin hypersensitivity
Dental medicine |
Others
NO
The aim of this study is to investigate the effectiveness of CAREDYNE SHIELD for dentin hypersensitivity by comparing with that of Nanoseal
Efficacy
The difference between preoperative and 4-weeks postoperative hypersensitivity score (VRS) to air stimuli
Interventional
Parallel
Randomized
Individual
Single blind -participants are blinded
Active
2
Treatment
Medicine |
CAREDYNE SHIELD will be applied once according to the manual and 4-weeks follow-up will be performed.
Nanoseal will be applied once according to the manual and 4-weeks follow-up will be performed.
20 | years-old | <= |
Not applicable |
Male and Female
1. outpatients
2. individuals who presented with a hypersensitivity complaint
3. individuals who agreed to attend this study after informed consent
1. individuals who have hypersensitivity to Zinc, CAREDYNE SHIELD or Nanoseal
2. individuals who presented with not only hypersentivity complaint but also other type of pain complaint
3. pregnant or lactating women
4. presence of caries at dentin-hypersensitivity teeth
5. presence of restoration at the dentin hypersentivity area
6. periodontal surgery and orthodontic treatment to dentine-hypersensitive teeth within the last 3 months
7. dentin-hypersensitivity teeth with advanced periodontal disease
8. treatment of dentin hypersensitivity within the last 6 months
9. presence of systemic conditions that mislead the results of this study (e.g. gastro-oesophageal reflux disease)
40
1st name | Takashi |
Middle name | |
Last name | MATSUURA |
Nagasaki University
Department of Periodontology and Endodontology, Nagasaki University Graduate School of Biomedical Sciences
852-8588
852-8588, 1-7-1, Sakamoto, Nagasaki, Nagasaki, Japan
095-819-7683
matsuurat@nagasaki-u.ac.jp
1st name | Takashi |
Middle name | |
Last name | MATSUURA |
Nagasaki University
Department of Periodontology and Endodontology, Nagasaki University Graduate School of Biomedical Sc
852-8588
852-8588, 1-7-1, Sakamoto, Nagasaki, Nagasaki, Japan
095-819-7683
matsuurat@nagasaki-u.ac.jp
Nagasaki University
Nagasaki University
Other
General Affairs Division, Nagasaki University Hospital
852-8588, 1-7-1, Sakamoto, Nagasaki, Nagasaki, Japan
095-819-7229
gaibushikin@ml.nagasaki-u.ac.jp
NO
2019 | Year | 09 | Month | 22 | Day |
https://pubmed.ncbi.nlm.nih.gov/32493500/
Published
https://pubmed.ncbi.nlm.nih.gov/35843957/
40
From November 2019 to April 2021, 24 participants with 40 teeth were enrolled in this study and 33 teeth in
20 participants were assessed at 4 weeks after treatment. A significant reduction of pain in response to air stimuli was
observed in both groups; however, no significant difference was observed between the groups.
2022 | Year | 08 | Month | 20 | Day |
participants who presented with a complaint of cervical dentine hypersensitivity
Forty CDH teeth which matched the eligibility criteria were randomly allocated to two groups in a 1:1 ratio: the CAREDYNE Shield group (intervention group) and the Nanoseal group (control group). The pain intensity in response to air stimuli, gingival condition, and oral hygiene status of CDH teeth were assessed before and at 4 weeks after treatment.
no harm was observed for any participant in this study.
The primary outcome was the reduction of pain intensity in response to air stimuli from baseline to 4 weeks after intervention.
Completed
2019 | Year | 09 | Month | 21 | Day |
2019 | Year | 10 | Month | 22 | Day |
2019 | Year | 11 | Month | 19 | Day |
2021 | Year | 04 | Month | 27 | Day |
2019 | Year | 09 | Month | 21 | Day |
2022 | Year | 08 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000043331
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |