Unique ID issued by UMIN | UMIN000039021 |
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Receipt number | R000044497 |
Scientific Title | Evaluation of intratumoral expression of chemotherapy-associated biomarkers for postoperative adjuvant chemotherarpy against advanced stage lung cancer |
Date of disclosure of the study information | 2020/02/20 |
Last modified on | 2023/08/16 08:00:04 |
Evaluation of intratumoral expression of chemotherapy-associated biomarkers for postoperative adjuvant chemotherarpy against advanced stage lung cancer
Evaluation of expression of chemotherapy-associated biomarkers
Evaluation of intratumoral expression of chemotherapy-associated biomarkers for postoperative adjuvant chemotherarpy against advanced stage lung cancer
Evaluation of expression of chemotherapy-associated biomarkers
Japan |
lung cancer
Pneumology | Chest surgery |
Malignancy
NO
We have performed tailor-made chemotherapy based on several chemotherapy-associated biomarkers for non-small cell lung cancer patients. In order to improve clinical outcome of advanced stage lung cancer, we plan to perform a prospective study on postoperative tailor-made chemotherapy based on chemotherapy-associated biomarkers using immunohistochemical evaluations of these biomarkers.
Efficacy
postoperative recurrece-free survival
overall survival
recurrent site and recurrent type
Interventional
Single arm
Non-randomized
Open -no one is blinded
Historical
1
Diagnosis
Other |
Evaluation of chemotherapy-associated biomarkes
Not applicable |
Not applicable |
Male and Female
1) pathologically diagnosed as advanced stage (stage II to III) non-small cell lung cancer
2) completely resected by surgery
3) under 75 years-old with PS 0 to 2, more than 74 years-old with PS 0 to1
4) laboratory data with 14 days before registration
(1) neutrolophil count > 1,500 /mm3
(2) platelet count > 100,000 /mmm3
(3) total bililubin < 2.0 mg/dl
(4) AST (GOT) < 100 U/L
(5) ALT (GPT) < 100 U/L
(6) serum creatinin < twice of upper limit of normal range
5) with informed consent from patient
1) with rejection from patient
2) inproper for registrtion judged by medical doctor
75
1st name | Cheng-long |
Middle name | |
Last name | Huang |
Kitano hospital
Department of Thoracic Surgery
530-8480
2-4-20 Ohgimachi, Kita-Ku, Osaka
06-6312-1221
chuang@kitano-hp.or.jp
1st name | Cheng-long |
Middle name | |
Last name | Huang |
Kitano hospital
Department of Thoracic Surgery
530-8480
2-4-20 Ohgimachi, Kita-Ku, Osaka
06-6312-1221
chuang@kitano-hp.or.jp
Kitano hospital
kitano hospital
Self funding
Kitano Hospital
2-4-20 Ohgimachi, Kita-Ku, Osaka
06-6312-1221
rinshou@kitano-hp.or.jp
NO
2020 | Year | 02 | Month | 20 | Day |
Unpublished
Preinitiation
2019 | Year | 12 | Month | 25 | Day |
2020 | Year | 03 | Month | 01 | Day |
2028 | Year | 03 | Month | 31 | Day |
Cases will be selectively registered.
2019 | Year | 12 | Month | 27 | Day |
2023 | Year | 08 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000044497
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