Unique ID issued by UMIN | UMIN000039046 |
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Receipt number | R000044527 |
Scientific Title | Observational study for ischemic penumbra using advanced MRI technology |
Date of disclosure of the study information | 2020/03/01 |
Last modified on | 2023/07/07 11:16:22 |
Observational study for ischemic penumbra using advanced MRI technology
Ischemic penumbra imaging
Observational study for ischemic penumbra using advanced MRI technology
Ischemic penumbra imaging
Japan |
Acute ischemic stroke
Neurology | Neurosurgery | Emergency medicine |
Adult |
Others
NO
To assess lesion of ischemic penumbra using quantitative susceptibility mapping
Others
Property of ischemic penumbra using advanced MRI technology
Correlation of quantitative susceptibility mapping with dynamic susceptibility contrast-derived ischemic penumbra tissues
Correlation of quantitative susceptibility mapping with National Institutes of Health Stroke Scale scores scores
Observational
18 | years-old | <= |
90 | years-old | > |
Male and Female
Patients with acute stroke diagnosed by MRI
Contraindication for MRI
40
1st name | Yuto |
Middle name | |
Last name | Uchida |
Toyokawa City Hospital
Neurology
442-0857
23 Noji, Yawata, Toyokawa, Aichi
0533-86-1111
uchidayuto0720@yahoo.co.jp
1st name | Shinobu |
Middle name | |
Last name | Kito |
Toyokawa City Hospital
Institutional Review Board
467-8601
23 Noji, Yawata, Toyokawa, Aichi
0533-86-1111
kitomrn@toyokawa-ch-aichi.jp
Toyokawa City Hospital
Toyokawa City Hospital
Other
Toyokawa City Hospital
23 Noji, Yawata, Toyokawa, Aichi
0533-86-1111
kitomrn@toyokawa-ch-aichi.jp
NO
2020 | Year | 03 | Month | 01 | Day |
doi: 10.3389/fneur.2022.752450
Partially published
doi: 10.3389/fneur.2022.752450
21
In these patients, the volumes with increased OEF values of>51.5%, which was defined using the anterior circulation territory OEF values from the 21 healthy controls, were positively correlated with the ischemic penumbra volumes and inversely correlated with the 30-day change in the National Institutes of Health Stroke Scale scores.
2023 | Year | 07 | Month | 07 | Day |
This prospective imaging study included 21 patients with
large anterior circulation vessel occlusion who were admitted <24 h after stroke onset
and 21 age-matched healthy controls.
We identified the ischemic penumbra as the region
with a Tmax of>6 s during dynamic susceptibility contrast-magnetic resonance imaging
(DSC-MRI) and calculated the perfusion-core mismatch ratio between the ischemic
penumbra and infarct core volumes. The OEF values were measured based on magnetic
susceptibility differences between the venous structures and brain tissues using rapid
QSM acquisition. Volumes with increased OEF values were compared to the ischemic
penumbra volumes using an anatomical template.
None
In these patients, the volumes with increased OEF values of>51.5%, which was defined using the anterior circulation territory OEF values from the 21 healthy controls, were positively correlated with the ischemic penumbra volumes and inversely correlated with the 30-day change in the National Institutes of Health Stroke Scale scores.
No longer recruiting
2020 | Year | 01 | Month | 03 | Day |
2020 | Year | 01 | Month | 03 | Day |
2020 | Year | 03 | Month | 01 | Day |
2020 | Year | 09 | Month | 30 | Day |
2020 | Year | 09 | Month | 30 | Day |
2020 | Year | 09 | Month | 30 | Day |
2020 | Year | 11 | Month | 01 | Day |
N.A.
2020 | Year | 01 | Month | 03 | Day |
2023 | Year | 07 | Month | 07 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000044527
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