Unique ID issued by UMIN | UMIN000039514 |
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Receipt number | R000045048 |
Scientific Title | Effects of combined consumption of catechins and chlorogenic acids on postprandial glucose, insulin, incretin response and insulin sensitivity in healthy men: a randomized, double-blind, placebo-controlled crossover trial |
Date of disclosure of the study information | 2020/02/29 |
Last modified on | 2020/02/17 15:58:52 |
Effects of combined consumption of catechins and chlorogenic acids on postprandial glucose, insulin, incretin response and insulin sensitivity in healthy men: a randomized, double-blind, placebo-controlled crossover trial
Effects of combined consumption of catechins and chlorogenic acids [n2016003]
Effects of combined consumption of catechins and chlorogenic acids on postprandial glucose, insulin, incretin response and insulin sensitivity in healthy men: a randomized, double-blind, placebo-controlled crossover trial
Effects of combined consumption of catechins and chlorogenic acids [n2016003]
Japan |
Healthy adults
Not applicable | Adult |
Others
NO
Evaluation of efficacy of combinational intake of catechins and chlorogenic acids on glucose metabolism
Efficacy
Blood glucose
Insulin, GLP-1, GIP, HOMA-R, Matsuda Index
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Placebo
NO
NO
NO
No need to know
2
Treatment
Food |
Control food 3 weeks consumption > wash out 2 weeks > test food 3 weeks consumption
Test food 3 weeks consumption > wash out 2 weeks > control food 3 weeks consumption
20 | years-old | <= |
60 | years-old | > |
Male
(1) Age >= 20 and < 60years
(2) Subjects who have given written informed consent prior to start of study
(1) Subjects having diabetes
(2) Subjects who have a history or signs of a heart or cerebrovascular disease
(3) Subjects having diabetes, a liver, kidney or respiratory disease, endocrine disorder, metabolic disorder, organ disorder, gout, rheumatism, autoimmune disease, allergy disease, mental disorder, cancer, infection disease, or other diseases
(4) Subjects who take an antidiabetic drug or antihyperlipidemic drug
(5) Subjects having thyroid deficiency
(6) Subjects who have a smoking habit
(7) Heavy drinker
(8) Subjects who have donated over 200 mL of blood within the last one month prior to the current study or over 400 mL of blood within the last three months prior to the study
(9) Subjects who have severe anemia (Hb <=7 g/dL)
(10) Subjects who have allergic reaction to food
(11) Subjects who are judged to be inappropriate for the study by the medical doctor or investigator for other reason
20
1st name | Noriko |
Middle name | |
Last name | Osaki |
Kao Corporation
Health & Wellness Products Research Laboratories
131-8501
2-1-3, Bunka, Sumida-ku, Tokyo, 131-8501, Japan
03-5630-7265
osaki.noriko@kao.com
1st name | Aya |
Middle name | |
Last name | Yanagimoto |
Kao Corporation
Biological Science Research laboratories
131-8501
2-1-3, Bunka, Sumida-ku, Tokyo, 131-8501, Japan
03-5630-7476
yanagimoto.aya@kao.com
Kao Corporation
Kao Corporation
Profit organization
Human Research Ethics Committee, Kao Corporation
2-1-3, Bunka, Sumida-ku, Tokyo, 131-8501, Japan
03-5630-7263
morisaki.naoko@kao.com
NO
2020 | Year | 02 | Month | 29 | Day |
Unpublished due to the protocol including the intellectual property rights
Published
works in progress
11
A significant difference was observed in the primary outcome.
2020 | Year | 02 | Month | 17 | Day |
Healthy adults
11 participants completed and 11 subjects were incorporated into the analyses
No adverse effect reported
Blood glucose
Main results already published
2016 | Year | 09 | Month | 08 | Day |
2016 | Year | 09 | Month | 08 | Day |
2016 | Year | 09 | Month | 26 | Day |
2016 | Year | 12 | Month | 08 | Day |
2017 | Year | 01 | Month | 17 | Day |
2017 | Year | 01 | Month | 20 | Day |
2017 | Year | 01 | Month | 23 | Day |
2020 | Year | 02 | Month | 17 | Day |
2020 | Year | 02 | Month | 17 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000045048
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Research case data | |
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