Unique ID issued by UMIN | UMIN000040403 |
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Receipt number | R000046101 |
Scientific Title | Investigation of disease-specific neuroimaging profiles of chronic pain using microglia PET and multimodal MRI |
Date of disclosure of the study information | 2020/05/14 |
Last modified on | 2020/05/14 19:03:19 |
Brain science of chronic pain using PET and MRI
Neuroimaging of chronic pain
Investigation of disease-specific neuroimaging profiles of chronic pain using microglia PET and multimodal MRI
Microglia PET/MRI study in chronic pain
Japan |
fibromyalgia, chronic low back pain, postherpetic neuralgia, other chronic pain disorders
Anesthesiology | Adult |
Others
NO
To determine cerebral pathophysiological changes in chronic pain using PET imaigng of microglia activation and multimodal MRI of brain anatomy and function.
Others
Correlation analysis among multimodal imaging and psychophysical parameters.
Intensity and distribution of microglia activation, as well as functional/anatomical activation/connectivity, in the brain of chronic pain patients in comparison with healthy controls.
Observational
20 | years-old | <= |
75 | years-old | >= |
Male and Female
Patients with chronic pain at a pain score >= 3/10 lasting >= 3 months (fibromyalgia, n = 15; chronic low back pain, 15; postherpetic neuralgia, 15; other chronic pain disorders, 15; healthy controls, 20)
Any person with in-body metals or electrical devices; tattoo; pregnancy; claustrophobia; or neurocognitive or consciousness disorder preventing informed consent
80
1st name | Jiro |
Middle name | |
Last name | Kurata |
Jikei University
Department of Anesthesiology
105-8461
3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo
03-3433-1111
jkurata@plum.plala.or.jp
1st name | Jiro |
Middle name | |
Last name | Kurata |
The Jikei University School of Medicine
Department of Anesthesiology
105-8461
3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo
03-3433-1111
jkurata@plum.plala.or.jp
The Jikei University School of Medicine
Japan Society for the Promotion of Science
Japanese Governmental office
The Ethics committee of The Jikei University School of Medicine for Biomedical Research
3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo
03-3433-1111
rinri@jikei.ac.jp
NO
東京慈恵会医科大学(東京都)、浜松医科大学(静岡県)
2020 | Year | 05 | Month | 14 | Day |
Unpublished
Preinitiation
2020 | Year | 05 | Month | 11 | Day |
2020 | Year | 06 | Month | 01 | Day |
2025 | Year | 03 | Month | 31 | Day |
The current study is a cross-sectional observational study performing correlational analyses among PET, MRI and psychophysical/behavioral parameters.
2020 | Year | 05 | Month | 14 | Day |
2020 | Year | 05 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046101
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