Unique ID issued by UMIN | UMIN000040587 |
---|---|
Receipt number | R000046321 |
Scientific Title | The analysis of COVID-19 in saliva, gastric fluid and intestinal fluid on gastrointestinal endoscopy |
Date of disclosure of the study information | 2020/06/01 |
Last modified on | 2021/11/25 05:16:16 |
The analysis of COVID-19 in saliva, gastric fluid and intestinal fluid on gastrointestinal endoscopy
The analysis of COVID-19 on gastrointestinal endoscopy
The analysis of COVID-19 in saliva, gastric fluid and intestinal fluid on gastrointestinal endoscopy
The analysis of COVID-19 on gastrointestinal endoscopy
Japan |
Participants who receive endoscopy
Gastroenterology |
Others
NO
To investigate the positive rate of COVID-19 in saliva, gastric fluid and intestinal fluid on gastrointestinal endoscopy
Safety
The positive rate of COVID-19 in saliva, gastric fluid and intestinal fluid on gastrointestinal endoscopy
The value of COVID-19 antibody
The purpose of endoscopy
The patients background
Observational
20 | years-old | <= |
Not applicable |
Male and Female
The all patients who receive endoscopy
COVID-19 suspected from questionnaire and medical interview
Not willing to participate this study
Emergency endoscopy
500
1st name | Takuma |
Middle name | |
Last name | HIGURASHI |
Yokohama City University
Department of gastroenterology and hepatology
236-0004
3-9 Fukuura, Kanazawaku, Yokohama, Kanagawa, Japan
045-787-2800
takuma_h@yokohama-cu.ac.jp
1st name | Takuma |
Middle name | |
Last name | HIGURASHI |
Yokohama City University
Department of gastroenterology and hepatology
222-0037
3-9 Fukuura, Kanazawaku, Yokohama, Kanagawa, Japan
045-787-2800
takuma_h@yokohama-cu.ac.jp
Yokohama City University
Yokohama City University
Self funding
Yokohama City University Hospital IRB
3-9 Fukuura, Kanazawaku, Yokohama, Kanagawa, Japan
045-787-2800
rinri@yokohama-cu.ac.jp
NO
2020 | Year | 06 | Month | 01 | Day |
https://doi.org/10.1111/den.13945
Published
https://doi.org/10.1111/den.13945
792
Results: A total of 783 samples (560 upper GIE and 223 lower GIE samples) were analyzed. Polymerase chain reaction (PCR) on saliva samples did not show any positive results in either upper or lower GIE samples. However, 2.0% (16/783) of gastrointestinal fluid samples tested positive for SARS-CoV-2. No significant differences in age, sex, purpose of endoscopy, medication, or rate of antibody test positivity were found between PCR positive and PCR negative cases.
2021 | Year | 02 | Month | 27 | Day |
2021 | Year | 02 | Month | 06 | Day |
The study was a single-center cross-sectional study. From June 1 to July 31, 2020, all patients who underwent GIE at Yokohama City University Hospital were registered. All patients provided 3 mL of saliva. For upper GIE, 10 mL of gastric fluid was collected through the endoscope. For lower GIE, 10 mL of intestinal fluid was collected through the endoscope.
The study was a single-center cross-sectional study. From June 1 to July 31, 2020, all patients who underwent GIE at Yokohama City University Hospital were registered. All patients provided 3 mL of saliva. For upper GIE, 10 mL of gastric fluid was collected through the endoscope. For lower GIE, 10 mL of intestinal fluid was collected through the endoscope.
none
The primary outcome was the positive rate of SARS-CoV-2 in saliva and gastrointestinal fluids. We also analyzed serum-specific antibodies for SARS-CoV-2 and patients' background information.
Main results already published
2020 | Year | 05 | Month | 13 | Day |
2020 | Year | 05 | Month | 13 | Day |
2020 | Year | 06 | Month | 01 | Day |
2020 | Year | 07 | Month | 31 | Day |
2020 | Year | 08 | Month | 31 | Day |
2020 | Year | 09 | Month | 14 | Day |
Observational study
2020 | Year | 05 | Month | 29 | Day |
2021 | Year | 11 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046321
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |