Unique ID issued by UMIN | UMIN000040633 |
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Receipt number | R000046377 |
Scientific Title | The evaluation of prehabilitation and nutritional support in cancer patients with neoadjuvant therapy |
Date of disclosure of the study information | 2020/06/03 |
Last modified on | 2023/12/05 10:22:19 |
The evaluation of prehabilitation and nutritional support in cancer patients with neoadjuvant therapy
The evaluation of prehabilitation and nutritional support in cancer patients with neoadjuvant therapy
The evaluation of prehabilitation and nutritional support in cancer patients with neoadjuvant therapy
The evaluation of prehabilitation and nutritional support in cancer patients with neoadjuvant therapy
Japan |
gastric cancer, esophageal cancer, biliary cancer, pancreatic cancer
Gastrointestinal surgery | Hepato-biliary-pancreatic surgery |
Malignancy
NO
The purpose is to investigate the possibility of improving surgical outcomes and preventing sarcopenia by using prehabilitation and nutritional support during neoadjuvant therapy.
Safety,Efficacy
The change of 6 minutes walk test between before and after neoadjuvant therapy
a) Exercise therapy: 1) Exercise therapy completion rate, 2) Improvement rate of exercise assessment items, 3) Total number of steps per day during the period of exercise therapy
2-a) Improvement rate of walking speed (10m walk)
2-b) Improvement rate of grip strength
2-c) Improvement value of the Simplified Physical Performance Battery (SPPB)
2-d) Improvement value of Timed-up-and-go test (TUG)
2-e) Improvement value of SARC-F Japanese version questionnaire
b) Nutritional therapy: 1) Completion rate of nutritional supplements, 2) Average amount of food consumed, 3) Improvement rate of nutritional status assessment items
3-a) Improvement value of MNA-SF
3-b) Improvement rate of upper arm circumference
3-c) Improvement rate of upper arm muscle circumference
3-d) Improvement rate of triceps subcutaneous fat thickness
3-e) Improvement value of CONUT
3-f) Improvement value of PNI
3-g) Improvement value of GNRI
c) Chemo(radiation) therapy-related side effects
d) Perioperative complications
e) Tumor reduction (evaluated by Evans classification)
f) Postoperative adjuvant chemotherapy: Rate of postoperative adjuvant chemotherapy, days from surgery to first chemotherapy administration
Observational
20 | years-old | <= |
Not applicable |
Male and Female
The patient with cancer(stomach, esophagus, biliary tract, pancreas) who was planned for neoadjuvant therapy.
The patient with low ADL who have difficulty in exercising
The patient with dementia
The patient who may get worse comorbidities or primary diseases by performing exercise therapy.
The patient with severe diabetes
The patient with gastrointestinal obstruction
The patient who are not scheduled for surgery
The patient who was judged by the researcher to be inappropriate for this research.
30
1st name | Kimitaka |
Middle name | |
Last name | Tanaka |
Hokkaido university hospital
Department of gastroenterological surgery 2
060-8638
Kita-ku North 15 West 7, Sapporo, Hokkaido, Japan
011-706-7714
kimitaka.t@gmail.com
1st name | Kimitaka |
Middle name | |
Last name | Tanaka |
Hokkaido university hospital
Department of gastroenterological surgery 2
060-8638
Kita-ku North 15 West 7, Sapporo, Hokkaido, Japan
011-706-7714
kimitaka.t@gmail.com
Hokkaido University hospital
Department of gastroenterological surgery 2, Hokkaido University Faculty of Medicine.
Other
Hokkaido University Hospital institutional review board
Kita-ku North 14 West 5, Sapporo, Hokkaido, Japan
011-706-7636
crjimu@huhp.hokudai.ac.jp
NO
2020 | Year | 06 | Month | 03 | Day |
Unpublished
30
No longer recruiting
2020 | Year | 03 | Month | 06 | Day |
2020 | Year | 03 | Month | 23 | Day |
2020 | Year | 06 | Month | 20 | Day |
2023 | Year | 03 | Month | 31 | Day |
Nothing special
2020 | Year | 06 | Month | 02 | Day |
2023 | Year | 12 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046377
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