Unique ID issued by UMIN | UMIN000040772 |
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Receipt number | R000046560 |
Scientific Title | Development of Quantitative Software for Joint Space Narrowing Progression on Radiography for Rheumatoid Arthritis Patients on Tocilizumab |
Date of disclosure of the study information | 2020/06/22 |
Last modified on | 2022/06/20 14:26:06 |
Development of Software for Finger Joint Space Narrowing Progression for Rheumatoid Arthritis Patients on Drug Therapy
Development of Software for Joint Images
Development of Quantitative Software for Joint Space Narrowing Progression on Radiography for Rheumatoid Arthritis Patients on Tocilizumab
Development of Quantitative Software for Joint Space Narrowing Progression
Japan |
Rheumatoid arthritis
Clinical immunology | Radiology |
Others
NO
To examine if therapeutic effect can be predicted in a short period of time after administration of Tocilizumab for patients with rheumatoid arthritis
Others
Reproducibility of the software
To prove correlation in joint space narrowing progression between our proposed system and standard system from baseline to week 52.
To prove that our proposed system can show joint space narrowing (JSN) progression at week 52 is grater in those with greater JSN progression at week 24.
To show correlation in JSN progression between at week 52 and at week 24 using our proposed system.
To show JSN progression at week 52 is greater than that at week 24 using our proposed system.
To prove the group with higher disease activity at week 0 has significantly greater JSN than that with lower disease activity at followup.
Observational
20 | years-old | <= |
100 | years-old | > |
Male and Female
1. Those who have a confirmed diagnosis of rheumatoid arthritis based on the 2010 standard
2.Those who have completed one year of Tocilizumab treatment
3. Radiography of the hands at the start of treatment and at 24 and 52 weeks after the start of treatment
4. Those who do not refuse to participate in this research
1.Those with severe joint destruction-Steinbrocker Stage III (high altitude progression) or higher
2. In addition, the person who the research director judges to be inappropriate as a research target person
50
1st name | Tamotsu |
Middle name | |
Last name | Kamishima |
Faculty of Health Sciences, Hokkaido University
Dept. of Biomedical Science and Engineering
0600812
North-12, West-5, Kita-ku, Sapporo 060-0812, Japan
011-706-2824
ktamotamo2@hs.hokudai.ac.jp
1st name | Tamotsu |
Middle name | |
Last name | Kamishima |
Faculty of Health Sciences, Hokkaido University
Dept. of Biomedical Science and Engineering
060-0812
North-12, West-5, Kita-ku, Sapporo 060-0812, Japan
+81117062824
ktamotamo2@hs.hokudai.ac.jp
Faculty of Health Sciences, Hokkaido University
Chugai Pharmaceutical Co., Ltd.
Profit organization
Institutional Review Board of Hokkaido University Hospital
Kita14 Nishi5, Kita-ku, Sapporo, Hokkaido
011-706-7636
crjimu@huhp.hokudai.ac.jp
NO
2020 | Year | 06 | Month | 22 | Day |
Unpublished
Completed
2019 | Year | 11 | Month | 01 | Day |
2019 | Year | 11 | Month | 14 | Day |
2020 | Year | 07 | Month | 31 | Day |
2020 | Year | 09 | Month | 01 | Day |
Software analysis of radiographic images of hands performed at facilities participating in this study in the past, and comparison with clinical findings, blood test data, and treatment responsiveness.
2020 | Year | 06 | Month | 15 | Day |
2022 | Year | 06 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046560
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