Unique ID issued by UMIN | UMIN000041060 |
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Receipt number | R000046718 |
Scientific Title | Phenotyping study of fish allergy |
Date of disclosure of the study information | 2020/07/13 |
Last modified on | 2020/07/10 11:54:31 |
Phenotyping study of fish allergy
Phenotyping study of fish allergy
Phenotyping study of fish allergy
Phenotyping study of fish allergy
Japan |
Food allergy
Clinical immunology | Pediatrics |
Others
NO
We classify patients with fish allergy into phenotypes according to the presence or absence of sensitization to parvalbumin and collagen, and examine whether differ the species of fish and the cooking method, that can be ingested without allergic symptom, depending on the phenotype.
Efficacy
Exploratory
Others
Not applicable
Difference in the recipe of the yellowtail (raw, grilled fish, boiled fish) that induces allergic symptoms among the 4 phenotypes.
Differences in ingestible fish species, recipes, and positive rates of skin prick test among the four phenotypes.
Observational
Not applicable |
15 | years-old | >= |
Male and Female
Intended for those who meet all of the following criteria
・Male and female under 15 years old
・Two or more episodes of immediate allergic reaction or gastrointestinal symptom, which including FPIES, after ingestion of fish
・Persons who have written consent to participate in this study by their legal guardians
Patients who meet any of the following will not be included in this study:
・If we suspect ananisakis allergy, histamine poisoning, or psychogenicity
・If the subject has other serious complications and is not suitable for this study
20
1st name | Osamu |
Middle name | |
Last name | Natsume |
Hamamatsu University School of Medicine
Pediatric
431-3192
1-20-1 Handayama, Higashi-ku, Hamamatsu City, Shizuoka Prefecture
053-435-2312
allergy@hama-med.ac.jp
1st name | Osamu |
Middle name | |
Last name | Natsume |
Hamamatsu University School of Medicine
Pediatric
431-3192
1-20-1 Handayama, Higashi-ku, Hamamatsu City, Shizuoka Prefecture
053-435-2312
allergy@hama-med.ac.jp
Hamamatsu University School of Medicine
Hamamatsu University School of Medicine
Self funding
Hamamatsu University School of Medicine
1-20-1 Handayama, Higashi-ku, Hamamatsu City, Shizuoka Prefecture
053-435-2312
allergy@hama-med.ac.jp
NO
2020 | Year | 07 | Month | 13 | Day |
Unpublished
Open public recruiting
2020 | Year | 01 | Month | 01 | Day |
2020 | Year | 02 | Month | 28 | Day |
2020 | Year | 07 | Month | 07 | Day |
2023 | Year | 03 | Month | 31 | Day |
This study is a multi-institutional cross-sectional study and will be conducted between the 2020 and March 2023.
Blood test (component-specific IgE test) and a skin prick test will be conducted on children diagnosed with fish allergies.
On the day of registration, additional serum for blood tests will be collected and a questionnaire will be distributed. At a later date, a skin prick test will be conducted and questionnaires will be collected.
The result of blood tests (parvalbumin sIgE and collagen sIgE), positive or negative are used to classify phenotypes for fish allergies.
We examine the differences in the types of fish and the cooking methods that can be ingested without allergic symptom between the four phenotype of fish allergy.
2020 | Year | 07 | Month | 10 | Day |
2020 | Year | 07 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000046718
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